Tag: Microbiology-Immunology
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The Antibiotic That Takes the Bite Out of Lyme
A new Northwestern study shows piperacillin, an antibiotic, effectively cured mice of Lyme disease at a dose 100 times smaller than the effective dose of doxycycline, the current gold-standard treatment.
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Post-Treatment Lyme Disease Syndrome May Be Driven by Remnants of Infection
A new Northwestern study may explain why the body may continue to respond to an invisible threat long after bacterial death in Lyme disease.
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Novel Mechanisms Help Lethal Bacteria Recognize and Infect Cells
Scientists led by Karla Satchell, PhD, have discovered previously unknown molecular mechanisms that help a type of foodborne bacteria called Vibrio vulnificus recognize host cells and initiate infection, according to a recent study published in Science Advances.
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Microbial Therapy Offers New Hope for Vitiligo Patients
A natural compound derived from gut-friendly bacteria can significantly slow the progression of vitiligo and may restore pigmentation, according to a new study.
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Delayed Antibody Treatment May Improve Efficacy of mRNA Vaccines
Investigators led by Pablo Penaloza-MacMaster, PhD, associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA vaccination significantly improved vaccine efficacy in mice, according to findings published in The Journal of Clinical Investigation.
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Targeting T-cell Lipid Metabolism May Improve Cancer Immunotherapy
Investigators have discovered that targeting specific mechanisms linked to lipid metabolism in immune cells within tumors may improve response to current and future cancer immunotherapies, according to a recent study published in the journal Immunity.
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Uncovering Regulatory Mechanisms of T-cells in Chronic Inflammation
Northwestern Medicine scientists have discovered a new underlying mechanism that controls a specialized group of T-cells, findings that may serve as potential targets for treating inflammatory diseases and cancer, according to a recent study.
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Spike Mutations Help SARS-CoV-2 Infect the Brain
Northwestern Medicine scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system, according to recent findings.
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Intracellular Mechanisms Promote Spread of Deadly Bacterial Infection
Northwestern Medicine investigators have discovered novel protein mechanisms that promote the rapid spread of Vibrio vulnificus, a rare but lethal bacteria that can cause vibriosis and sepsis, according to findings published in Proceedings of the National Academy of Sciences.
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Weakened Virus Helps Eliminate Cancer
Northwestern Medicine scientists have discovered that a weakened form of a virus can be used to help eliminate cancer in mice.
