Tag: Cancer
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Localized Genetic Mutations May Serve as Biomarker for Wide Range of Cancers
Northwestern Medicine investigators have successfully localized novel molecular mechanisms behind a genetic mutation found in a wide range of cancers, which could serve as a biomarker for improving patient stratification and treatment, according to findings published in Proceedings of the National Academy of Sciences.
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Study Discovers Novel Biomarker for Vascular Aging and Neurodegeneration
Decreased activity of a specific signaling pathway in the brain vessels of aging mice and humans was linked to a decline in vascular function and subsequent neurodegeneration, according to a recent Northwestern Medicine study published in the Journal of Clinical Investigation.
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AI May Spare Breast Cancer Patients Unnecessary Treatments
A new AI tool may make it possible to spare breast cancer patients unnecessary chemotherapy treatments by using a more precise method of predicting their outcomes, reports a new Northwestern Medicine study published in Nature Medicine.
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Drug Extends Survival in Prostate Cancer with Genetic Mutations
Men with hormone-resistant prostate cancer and specific genetic mutations who were treated with the drug olaparib survived longer than men treated with traditional hormone therapy, according to a post hoc analysis published in the Journal of Clinical Oncology.
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Using Gene Expression to Predict if a Brain Tumor is Likely to Grow Back
Scientists have found a highly accurate way to predict the best cancer treatment for patients based on patterns of gene expression in their tumors.
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Pioneering Automated Proteoform Imaging
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
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Exploring Transcription Elongation Control in Development, Disease and Aging
In a recent article published in Molecular Cell, the laboratory of Ali Shilatifard, PhD, provided a comprehensive overview of the current understanding of the elongation stage of DNA transcription and how its dysregulation is associated with developmental defects, disease and aging.
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Novel Therapy Extends Survival in Metastatic Cancer
Northwestern Medicine investigators have identified a novel therapeutic agent that is effective in treating metastatic cancer and brain metastases, according to a recent study published in the Journal of Clinical Investigation.
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Improving Nanotherapeutic Vaccine Delivery
Northwestern Medicine scientists have developed a more effective way of creating nanotherapeutic vaccines and medicines, according to a study published in ACS Nano.
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Study Identifies Genetic Cause for Some Brain Tumors
Scientists have uncovered a genetic explanation for a subset of common brain tumors, according to a study published in Nature Communications.
