Tag: Cancer
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Targeting Protein Interactions May Boost Antitumor Immunity in Breast Cancer
A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses, according to findings published in the Journal of Clinical Investigation.
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Cancer Drug Trial Provides Lessons for Future
A cancer drug was found to be ineffective in preventing recurrence of kidney cancer in patients who recently underwent tumor removal surgery, according to a clinical trial published in the Journal of Clinical Oncology.
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MRI Surveillance Significantly Reduces Breast Cancer Mortality
Women with breast cancer who carried the BRCA1 breast cancer mutation and who were enrolled in an MRI surveillance program saw an 80 percent reduction in breast cancer mortality compared to those who did not undergo MRI surveillance, according to findings published in JAMA Oncology.
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Developing Tools to Explore DNA Methylation
A Northwestern Medicine study has detailed the development of a machine learning model to predict DNA methylation status in cell-free DNA by its fragmentation patterns, according to findings published in Nature Communications.
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Potential Therapeutic Target for Small Cell Lung Cancer Discovered
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer cells may decrease cancer cell differentiation and tumor growth, according to findings published in Nature Communications.
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Novel Mechanism Supports Antitumor Response and T-cell Survival
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
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Predicting Infection Risk in Childhood Cancer
A model can accurately predict the risk of bloodstream infections in a subset of children with cancer, according to a study published in the Journal of Clinical Oncology.
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Investigating Mechanisms of Aggressive Glioblastoma Tumor Growth
Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature Communications.
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Novel Immune Inhibitor Associated with Glioma Progression
Northwestern Medicine investigators led by Amy Heimberger, MD, PhD, have discovered a new mechanism in which cancer-associated fibroblasts are associated with tumor grade and mediate immune suppression in glioma tumors.
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Examining Infection Rates in Prostate Cancer Biopsies
Two methods of prostate cancer biopsy demonstrated similar, minimal rates of infection in patients with prostate cancer, according to a recent Northwestern Medicine study published in the journal European Urology.
