
A new Northwestern Medicine study reports that DNA manifested as knot-like folds and third rungs between DNA’s two strands may drive cancer development and an important regulatory enzyme could be associated with the formation of these unusual structures.

A team of investigators have discovered a novel genomic variant that may help clinicians predict which patients will experience cardiotoxicity from a widely used chemotherapy drug, according to a Northwestern Medicine study.

A recent study showed that targeted radioembolization alongside chemotherapy improved progress-free survival for patients with metastatic colon cancer.

Mutations in a histone regulator protein are connected to both a rare neurodevelopmental disorder and to some cancers, according to a recent study.

Northwestern Medicine scientists have discovered a new biomarker to identify which patients with brain tumors called glioblastomas — the most common and malignant of primary brain tumors — might benefit from immunotherapy.

Scientists have discovered a potential biomarker that could more accurately identify which patients with non-hypermutated cancers will respond to specialized immunotherapy drugs.

A previously unknown mechanism involving the protein Scribble helps maintain polarity in cells, according to a Northwestern Medicine study.

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells — opening the door to dual inhibition, according to a recent Northwestern Medicine study.

The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a Merit Extension Award from the National Cancer Institute, one of only two Comprehensive Cancer Centers in the nation to earn the recognition.