
A new study shows that pancreatic tumors use a sugar-based disguise to hide from the immune system, and Northwestern scientists have also created an antibody therapy that blocks the “don’t-attack” signal.

Northwestern Medicine scientists have discovered how a specific transcription factor promotes genetic reprogramming and chemotherapy resistance in ovarian cancer cells, findings that may inform new targeted treatment approaches that inhibit this process and improve patient outcomes, according to a recent study published in The Journal of Clinical Investigation.

A team of Northwestern investigators has discovered novel molecular underpinnings of a common oncogenic mutation in cancer, findings that may inform the development of new therapeutic strategies, according to findings published in Nature Chemical Biology.

Biological markers may help predict which patients will benefit most from specific therapies to treat prostate cancer, according to a study published in the journal Cell.

A novel approach to detect RNA modification patterns in patient blood samples may be a promising tool for the early detection of colon cancer, as detailed in a recent study published in Nature Biotechnology.

In a pair of studies, investigators from the lab of Huiping Liu, MD, PhD, have uncovered how specific cellular interactions in the bloodstream may be fueling the spread of breast cancer.

Feinberg investigators now have access to one of the most advanced super-resolution imaging systems in the world, thanks to the installation of the MIRAVA Polyscope at the Center for Advanced Microscopy.

Scientists at Feinberg are reshaping scientific understanding of the cell’s tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life.

Scientists in the laboratory of Weiguo Cui, PhD, have identified novel molecular mechanisms that help specialized T-cells maintain long-term immunity in response to chronic infection and cancer, according to recent findings published in Nature Immunology.

A new Northwestern Medicine study has uncovered a surprising molecular link between HIV-1 and a protein fragment associated with Alzheimer’s disease, according to findings published in the Proceedings of the National Academy of Sciences.