Tag: Cancer
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Study Identifies Potential Therapeutic Target for Colon Cancer
Northwestern Medicine scientists have discovered that inhibiting the GATA6 protein in mouse models of colon cancer reduced tumor growth and improved survival, underscoring the potential of a new therapeutic target for colon cancer, according to a recent study published in Science Advances.
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Blood-Brain Barrier Disruption Reveals Genetic and Structural Changes in Neurological Diseases
Northwestern Medicine investigators have discovered unique genetic and structural changes in endothelial cells in the brain after disrupting the blood-brain barrier, which may inform new therapeutic targets that promote blood-brain barrier repair after neurovascular injuries, according to a recent study.
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Reprogramming Compromised Immune Cells to Fight Cancer
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to work against tumors, according to a study published in Science Advances.
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Uncovering the Molecular Drivers of B-cell Lymphoma Tumor Growth
Northwestern Medicine scientists have uncovered a key pathway controlling tumor growth in B-cell lymphomas, according to a study published in the Journal of Clinical Investigation.
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Investigating New Treatments for Rare Skin Lymphomas
A fusion protein therapy may be an effective treatment option for cutaneous T-cell lymphomas, according to a multicenter clinical trial published in the Journal of Clinical Oncology.
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Novel Technique May Accelerate Study of Gene Regulation
Investigators from the laboratory of Ali Shilatifard, PhD, have developed a novel technique to precisely and efficiently study gene regulation, which may accelerate the development of new therapeutic strategies, according to a recent study published in Molecular Cell.
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Unravelling the Mysteries of Calcium Channel Regulation
Scientists have uncovered new insights into the molecular players behind calcium channel regulation, a biological process that coordinates a wide array of physiological responses, according to a study published in the Proceedings of the National Academy of Sciences.
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Active Surveillance of Prostate Cancer On the Rise
The use of active surveillance and watchful waiting increased from 13.2 percent in 2010 to 53.8 percent in 2020 among patients with intermediate-risk prostate cancer, according to a recent study published in JAMA.
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Unlocking New Possibilities for Cancer Immunotherapy
Northwestern Medicine scientists have developed a method for identifying reactive cysteines on peptide antigens within the immune system, a development which may prove useful in cancer immunotherapy, according to a study published in Nature Communications.
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Blood Test May Reduce Unnecessary Prostate Cancer Biopsies
A new blood test may help reduce unnecessary prostate biopsies and can detect prostate cancer with similar sensitivity to standard screening in patients across racial and ethnic groups, according to a recent study published in the Journal of Clinical Oncology.
