Tag: Biochemistry and Molecular Genetics
-
New DNA Identification Approach Could Improve Monitoring for Chronic Diseases
Investigators led by Shana Kelley, PhD, have developed a novel approach for identifying sequences of artificial DNA with differing levels of binding to other small molecules, which could improve diagnostic monitoring for patients with chronic diseases.
-
Study Discovers Novel Region for BRD4 Transcription and Potential Therapeutic Target
Northwestern Medicine investigators have discovered a novel protein region that regulates DNA transcription elongation, suggesting a new therapeutic target for treating cancers and developmental disorders, according to findings published in Molecular Cell.
-
Combining Epigenetic and Metabolic Approaches for Targeted Cancer Treatment
Northwestern Medicine scientists have identified a novel vulnerability in a subset of genes commonly mutated in cancer, according to a study recently published in The Journal of Clinical Investigation.
-
Understanding How Aggressive Thyroid Cancer Evolves
Northwestern Medicine scientists have shed new light on how the deadliest form of thyroid cancer becomes more aggressive, according to research published in the Journal of Clinical Investigation.
-
New Therapy Harnesses Patients’ Blood Cells to Fight Tumors
Northwestern University scientists have discovered it is possible to isolate a tumor’s attack cells non-invasively from blood, rather than from tumors.
-
CRISPR Pioneer Delivers Inaugural Kimberly Prize Lecture
Jennifer A. Doudna, PhD, the Li Ka Shing Chancellor’s Chair and professor in the Departments of Chemistry and of Molecular and Cell Biology at the University of California, Berkeley, delivered the inaugural Kimberly Prize in Biochemistry and Molecular Genetics Lecture to Feinberg faculty, staff and students on Tuesday, April 4.
-
New Combination of Drugs Works Together to Reduce Lung Tumors in Mice
Two therapeutic drugs benefited mice with non-small cell lung cancer, potentially paving the way for clinical trials in humans.
-
New Gene Implicated in Cancer, Cellular Stress Response
Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity.
-
New Gene Target for Aggressive Lung Cancer Discovered
Northwestern Medicine scientists have identified a gene that is responsible for activating an aggressive subtype of small-cell lung cancer for which there is no current effective treatment.
-
Exploring Novel Mechanisms and Therapeutic Targets for Acute Myeloid Leukemia
Patients with acute myeloid leukemia show large-scale genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a Northwestern Medicine study published in Nature.
