Tag: Biochemistry and Molecular Genetics
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Study Shows Diabetes Drug Lowers Blood Sugar by Interfering With Mitochondria
A new study has provided direct evidence in mice that the drug reversibly cuts the cell’s energy supply by interfering with mitochondria to lower glucose levels.
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Shaking Sensor Continuously Monitors Inflammation
Northwestern University scientists have designed a new implantable device that can monitor fluctuating levels of proteins within the body in real time.
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Esteemed Molecular Biologist Named Winner of 2025 Kimberly Prize
Distinguished biochemist Ron Evans, PhD, director of the Gene Expression Laboratory and professor at the Salk Institute for Biological Studies, has been named the winner of the annual $250,000 Kimberly Prize in Biochemistry and Molecular Genetics.
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Understanding How Deadly Lung Cancers Control the Local Immune System
Northwestern Medicine scientists have discovered how a protein in a deadly type of lung cancer can control how the immune system responds to the tumor, according to a study published in the Proceedings of the National Academy of Sciences.
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Intercellular Mechanisms Regulate Gene Expression in Cancer Cells
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
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‘Feedback Loop’ Promotes Cancer Cells’ Adaption to Molecular Stress
Investigators from the laboratory of Marc Mendillo, PhD, have discovered new cellular regulators of an established cancer cell transcription factor linked to cancer cell resilience and tumor progression, according to findings published in the Proceedings of the National Academy of Sciences.
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Study Finds Noncoding RNAs Dysregulated in Several Human Cancers
Northwestern Medicine scientists have discovered new insights into the production and regulation of an emerging class of noncoding RNAs in three major types of cancer, according to findings published in Science Advances.
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Scientists Discover Potential Biomarker in Rare Skin Cancer
Northwestern Medicine scientists have discovered increased immune cell activity in Merkel cell carcinoma tumors, which could help predict treatment response in patients and inform the development of new targeted therapies, according to findings published in the journal Cancer Discovery.
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Mitochondria Support Immune Response to Central Nervous System Injuries
Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of immune cells called microglia, but do help them respond to demyelinating injury, according to a study published in Nature Metabolism.
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Understanding Inflammation in the Heart
Inflamed heart muscles can mount immune responses even in the absence of immune cells, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
