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New Biomarker May Predict Treatment Response in Bladder Cancer
Patients with metastatic urothelial cancer and increased expression of the NECTIN4 gene had a dramatically better response to antibody treatment than patients with reduced gene expression, according to recent findings published in the Journal of Clinical Oncology.
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Improving Models to Study the Human Heart
Northwestern Medicine scientists have developed a new method of measuring and optimizing the maturation process of cultured heart cells, an approach that will set the future standard for a commonly used cell model in scientific research, according to details published in Cell Reports.
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Gene Therapies Could Transform Treatment of Rare Blood Disorders
A new gene therapy could revolutionize treatment for two rare genetic blood disorders, according to a pair of trials published in the New England Journal of Medicine.
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Children With Skin Diseases Suffer Stigma, Bullying and Depression
A study has shown the majority of children and teens with chronic skin diseases feel stigmatized by peers for their condition, are sometimes bullied, and often suffer from depression and anxiety.
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Feinberg Faculty and Regulatory Affairs Welcomes New Senior Director
Joan Trimuel Williams has been named Feinberg’s senior director for Faculty and Regulatory Affairs.
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Tech Can’t Replace Human Coaches in Obesity Treatment
In obesity treatments, patients who only received technology assistance were less likely to show weight loss than those who also received help from a human coach, according to a new study.
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New Mechanisms Underlying Tumor Variety in Brain Cancers Discovered
Investigators have discovered new mechanisms underlying intratumor heterogeneity and treatment resistance in meningiomas, the most common type of primary central nervous system tumor, according to a recent study published in Nature Genetics.
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Novel Genetic Mechanisms May Serve as Therapeutic Target Against Glioma
A recent study from the laboratory of Shi-Yuan Cheng, PhD, has identified novel mechanisms underlying RNA splicing events within glioma tumor cells, mechanisms which may serve as novel therapeutic targets, according to findings published in The Journal of Clinical Investigation.
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Celebrating the MD Class of 2024
Feinberg honored the MD Class of 2024 during the medical school’s 165th commencement ceremony held in the Aon Grand Ballroom at Navy Pier on May 13.
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Honors Day Recognizes Student and Faculty Excellence
Faculty members and fourth-year medical students were recognized for academic and clinical excellence during Feinberg’s Honors Day, held on May 10 in the Hughes auditorium.
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Genetic Variation Linked to Increased Risk of Pick’s Disease
A unique genetic variation in the MAPT gene was associated with increased risk of Pick’s disease, a rare form of frontotemporal dementia, according to a recent study published in The Lancet Neurology.
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Leading Prostate Cancer Research for More than 20 Years
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center…
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How Herpes Hijacks a Ride into Cells
Northwestern Medicine scientists have discovered how herpes viruses hijack cellular transport processes to infiltrate the nervous system, according to a study published in the Proceedings of the National Academy of Sciences.
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Weight Loss Drug Shows Benefits for Heart Failure
Semaglutide, sold under brand names Ozempic and Wegovy, can help reduce heart failure symptoms and reduce heart failure hospitalizations in patients with obesity, according to a pair of studies published in The Lancet and The New England Journal of Medicine.
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Study Identifies Disparities in End-of-Life Care for Lung Cancer Patients
Patients with lung cancer who were Asian/Pacific Islander, Black or Hispanic experienced a higher intensity of end-of-life care compared to white patients, according to a Northwestern Medicine population-based analysis published in the Journal of Clinical Oncology.
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B-Cells May Play Role in Lung Transplant Rejection
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation that can lead to rejection, according to a study published in the Journal of Clinical Investigation.
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Drug Shows Promise for Starving Out Cancer Cells
Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a study published in Science Advances.
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Understanding Cellular Transcription Responses to Oxygen Deprivation
A multiprotein complex is essential for regulating cellular transcription response to oxygen deprivation, a key feature of cancer, according to a Northwestern Medicine study published in the Proceedings of the National Academy of Sciences.
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Skin Patch Improves Treatment for Pediatric Milk Allergies
Daily immunotherapy delivered via a dermal patch reduced risk of reactions, including anaphylaxis, in children with an immunoglobulin E (IgE)–mediated cow’s milk allergy, according to a recent clinical trial published in JAMA Pediatrics.
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Postdoc Rogan Grant named a Schmidt Science Fellow
Northwestern postdoctoral scholar Rogan Grant has been selected as a 2024 Schmidt Science Fellow, a program that sponsors promising, emerging scientists with postdoctoral placement in internationally renowned labs and promoting an intersectional approach to addressing global challenges.
