
A novel gene therapy promoted transfusion independence in more than 90 percent of adult and pediatric patients with transfusion-dependent beta-thalassemia. Study co-author Jennifer Schneiderman, MD, discusses results, published in the New England Journal of Medicine.

Man’s best friend is helping scientists find new treatments for brain tumors. Amy Heimberger, MD, is a board-certified neurosurgeon with extensive training and experience in the field of immunology. She is part of a promising new study in canine glioblastoma that could lead to more effective human glioblastoma clinical trials.

Music-based medical interventions can have remarkable therapeutic benefits for patients diagnosed with cognitive impairments such as Alzheimer’s disease, dementia and aphasia. Neurologist Borna Bonakdarpour, MD, explains how he is using and studying these clinical interventions through the new Northwestern Music and Medicine Program.

Accelerating new advances in the prevention, diagnosis and treatment of infectious diseases is an important goal of the Northwestern University Clinical and Translational Sciences Institute (NUCATS) and the past two years have been a crucial time for the study of infectious diseases. Richard D’Aquila, MD, professor of Medicine in the Division of Infectious Diseases at…

Nearly half of all patients with heart failure have preserved ejection fraction, or HFpEF, yet there is much that is unknown about HFpEF and how to best prevent it and treat it. Northwestern Medicine cardiologist, Sanjiv Shah, ’00 MD, leads the world’s first clinical program dedicated to the study of heart failure with HFpEF. He…

Since coming to Northwestern in 2013, Deborah Smith Clements, MD, chair of the Department of Family & Community Medicine, has established three thriving family medicine residency programs and has been an advocate for improving the residency match process, health policy and social justice. She talks about her work, leading her department through COVID-19 and her…

David Gate, PhD, discusses his study on the detrimental role the immune system plays in Lewy body dementias. This disease encompasses two disorders: Parkinson’s disease dementia and dementia with Lewy bodies. Actor Robin Williams famously passed away with dementia with Lewy bodies. NBA coach Jerry Sloan died of dementia with Lewy bodies as well. Gate’s…

Judith Moskowitz, a social psychologist and professor of Medical Social Sciences at Feinberg, talks about how her NIH-funded research and intervention programs will be used to address stress and burnout in Chicago’s front-line violence prevention workers.

In response to the first successful animal heart transplant into a human patient, internationally renowned transplant surgeon Satish Nadig, MD, PhD, reviews some of the scientific developments that have culminated in this moment and stresses the ongoing need for other experimental strategies. Nadig is also the new director of Feinberg’s Comprehensive Transplant Center.

When most of us think about dopamine, we think about reward signals. But new research from Northwestern Medicine, published in Nature Neuroscience, has found a genetic subtype of dopamine neurons that do not respond to rewards at all, and instead, fire when the body moves. Rajeshwar Awatramani, PhD, and Daniel Dombeck, PhD led this work,…