The work done by Northwestern University Feinberg School of Medicine faculty members (and even some students) is regularly highlighted in newspapers, online media outlets and more. Below you’ll find links to articles and videos of Feinberg in the news.
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According to PhRMA, the pharmaceutical industry research and advocacy group, the average drug takes over 10 years and $2.6 billion dollars to reach the market. The group also notes that only 12% of drugs entering clinical trials result in a medicine that’s approved by the U.S. Food and Drug Administration. Research and development of pharmaceuticals relies on a lot of trial and error, according to Yuan Luo, PhD, who is Director of the Institute for Artificial Intelligence in Medicine at Northwestern University’s Feinberg School of Medicine. “That’s a bet,” said Dr. Luo. “What if it failed? Then years of the investment got wasted.” Dr. Luo and other experts who watch the emerging field of AI in drug discovery said machines will help humans cut down on the time it takes to complete repeat tasks. “We can move the most promising candidates to clinical trials and save time and save resources,” said Dr. Luo. He said AI brings a huge shift to this space, allowing scientists to do less “wandering” and more discovering. “It’s sort of like a GPS,” Dr. Luo said. “It will take us to the neighborhood we are looking for, and also along the way advance our existing knowledge of the human biology.”
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Bauer entered a hospital with the flu, a bit of pneumonia in his lungs. However, the next day he couldn’t walk. The flu had turned into a lung infection resistant to antibiotics. On April 17, Bauer entered the intensive care unit at Saint Louis University Hospital. He was moved onto a ventilator, then into a medically induced coma. SLU Hospital refused to perform a lung transplant, saying Bauer was too sick to survive. After the hospital called the Northwestern Medicine Canning Thoracic Institute, the man and his girlfriend relocated to Chicago. Bauer’s surgery was “uncharted territory” for the program, said Dr. Rade Tomic, medical director of the Northwestern Medicine Canning Thoracic Institute Lung Transplant Program. “We knew that to get him listed (for a transplant), we had to resolve the infection,” Tomic said. “The only way to resolve the infection was actually taking the lungs out.” The surgical team removed Bauer’s infected lungs and cleaned out his chest cavity. To keep his body alive without lungs, the team needed to create channels for blood to flow in and out of his heart, said Dr. Ankit Bharat, chief of thoracic surgery and director of the Canning Thoracic Institute. That’s where a pair of DD breast implants came in. “We needed something to support his heart, and the DD breast implants seemed to be the perfect fit,” Bharat said. With Bauer’s heart stabilized between the implants, surgeons created an artificial lung outside Bauer’s body. The thoracic surgery team collaborated with plastic surgeons for a “crash course” on working with breast implants.
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The rapid test is finally, blissfully, negative after a week of dark red positives. You’re technically over Covid — but the virus doesn’t seem to be over you, as fatigue, coughing or a general sense of “blah” persists. If symptoms linger for four or more weeks after a negative test, that’s the point at which they could first be identified as long Covid, according to the Centers for Disease Control and Prevention. For most people, the immune system quiets down quickly after it fights Covid. For some, though, it stays active. Researchers are not entirely sure why this happens. If you’re still feeling poorly after 30 days, reach out to a primary care doctor, who may be able to offer strategies for managing your symptoms. You may also want to see if there is a medical facility, like a research hospital, that specializes in long Covid recovery near you, advised Marc Sala, MD, co-director of the Northwestern Medicine Comprehensive Covid-19 Center in Chicago.
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Hepatitis C cases have been rising in recent years, significantly impacting women of childbearing age. Hepatitis C can cause low birthweight, liver disorders and pre-term births in an infant. A medical challenge that exists with this virus is doctors not treating pregnant individuals who carry Hepatitis C until after they give birth, which is something Northwestern Medicine and Lurie Children’s Hospital is changing. Ravi Jhaveri, MD, head of pediatric infectious diseases at Lurie Children’s Hospital, shared more about Hepatitis C. “We recommend testing for Hepatitis C,” Jhaveri said. “Any time any adult sees their doctor, it should be part of their visit, especially during pregnancy.” Jhaveri said the medications developed to fight this virus are powerful, and can effectively cure any patient. “The treatment is once per day with very few side effects,” Jhaveri said. “We’re talking almost 100% of people being cured.” If Hepatitis C is not treated, Jhaveri said it can affect a person’s liver and the risk for fibrosis and cancer can go up.
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Everyone could use an extra hour of sleep. On Sunday, Nov. 5, most of the United States — except for Hawaii and most of Arizona, which don’t observe daylight saving time — will enjoy an extra hour of sleep, but is it actually a good thing? Although the day the clocks “fall back” gives you an extra hour of sleep before your alarm goes off, daylight saving time ending in November has multiple health implications. “Just that one hour can change the amount of sleep you get, the quality of sleep that you get,” Phyllis Zee, MD, PhD, a sleep researcher at Northwestern Medicine in Chicago, said per The Associated Press. “Off-kilter sleep can affect people’s ability to multitask, stay alert and even maintain their balance, making them more prone to accidents.” Many people, especially those with preexisting conditions, can experience darker moods following the clock change and through the fall and winter months.
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Next week across most of the US, the sun will set well before many folks step foot out of the office, leaving them to run errands or take walks in utter darkness. Come November 5, daylight saving time is out and standard time is in, and will last until March 10. Besides scheduling stumbles and sleep habit disruptions, experts say the twice-yearly ritual can have more serious effects on human health. Many Americans are already sleep-deprived, and a change in time messes with sleep schedules even more, says Phyllis Zee, MD, PhD, a sleep researcher at Northwestern Medicine in Chicago and professor of neurology (sleep medicine) at Northwestern University Feinberg School of Medicine, although she says “falling back” and gaining an extra hour is generally easier on the body than “springing forward” and losing one. “Just that one hour can change the amount of sleep you get, the quality of sleep that you get,” Zee said. Off-kilter sleep can affect people’s ability to multitask, stay alert, and even maintain their balance, making them more prone to accidents.
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Staying in sync with the sun is important to maintaining our circadian rhythms, sleep-wake cycles and overall health. Every morning, sunlight resets our internal clock to put us in sync with a 24-hour day. Then, after the sun sets, the lack of sunlight allows our bodies to produce hormones such as melatonin, which promotes sleep. Phyllis Zee, MD, PhD, a neurologist and chief of sleep medicine at Northwestern University’s Feinberg School of Medicine, said without that sunlight, we can slip into circadian misalignment — “when your internal body clocks fall out of sync with that of the sun clock and your social clocks.” This weekend, 48 states and the District of Columbia will reset their clocks and fall back into standard time. You may notice that you feel better with the time change and the extra morning sunlight it brings.
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Northwestern Medicine’s Women’s Infectious Disease Program is turning to an uncommon practice of treating hepatitis C in pregnant women, in an effort to stem the tide of rising infection rates for the disease. The standard of care for treating hepatitis C in a pregnant person is to initiate treatment immediately postpartum, a Northwestern Medicine statement said, but that approach has significant limitations. During pregnancy, hepatitis C has been associated with low birth weight, intrahepatic cholestasis of pregnancy and preterm birth, the statement said. “Our goal is pretty simple — we want to improve the lives of pregnant patients with hepatitis C and their infants,” Lynn Yee, a maternal-fetal medicine specialist and director of the Northwestern Medicine Women’s Infectious Disease Program, said in the statement. “Although treatment during pregnancy is not yet common, our professional societies support a shared decision-making process, including discussing with patients what is known versus unknown. We believe that by including pregnant people in hepatitis C research and treatment programs, we will work towards the public health goal of eliminating hepatitis C as well as addressing historical issues of excluding pregnant people from life-changing therapies.” Rising hepatitis C rates are driven by the ongoing opioid epidemic and the sharing of needles, the statement said.
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Thousands of migrants sleeping at police stations woke up to freezing cold conditions on Halloween morning as city officials, volunteers and faith-based organizations scrambled to find warmth Tuesday for a population, mostly from Venezuela, that has never experienced cold. Scott Dresden, MD, MS, an associate professor of emergency medicine at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician, said he wasn’t sure how the thousands of migrants that have arrived since last August would influence the numbers of people he treats in emergency departments over the next few months. “This is certainly a unique winter with a larger population who are without housing than we are used to,” he said. When someone has mild hypothermia they will start shivering, Dresden said. As the body shuts down, confusion will set in. The shivering will stop. He said severe hypothermia can cause cardiac arrest.
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When a cold or flu strikes, choosing among hundreds of products can be overwhelming. But to clear up a stuffy nose, doctors and pharmacists say consumers should choose medicine wisely. A key ingredient found in many over-the-counter medicines—oral phenylephrine—just doesn’t work, according to a finding last month by advisers to the Food and Drug Administration. A few weeks after that determination, CVS Health stopped selling certain oral medicines with the ingredient. There are plenty of convenient alternatives for relief from a cold or flu, but the first step is to consider your symptoms: Congestion? Congestion with a runny nose? “The most important thing is for people to always think about, ‘What is going on? What am I feeling?’ That helps you understand what’s best for you,” said Sterling Elliott, a clinical pharmacist and assistant professor of orthopedic surgery at Northwestern University Feinberg School of Medicine. There is one medicine that is the time-honored standard for relieving congestion from cold and flu: Pseudoephedrine. The decongestant shrinks blood vessels in the nasal area and prevents blood from flowing into them, stopping the congestion. “We know that it works because when people take it they certainly report benefit and relief,” said Elliott.