The work done by Northwestern University Feinberg School of Medicine faculty members (and even some students) is regularly highlighted in newspapers, online media outlets and more. Below you’ll find links to articles and videos of Feinberg in the news.
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Antibiotic resistance is a growing concern in the U.S., particularly when it comes to treating pediatric pneumonia. Doctors are now questioning whether antibiotics should be used at all for this condition. Chicago’s Lurie Children’s Hospital, in collaboration with the University of Utah Health, has been awarded $12 million to investigate this issue. Their study will compare two methods of using antibiotics for treating pneumonia in children. “When you think about the millions of children that are diagnosed with pneumonia in the United States each year and the millions of days of antibiotics that those children receive, often times unnecessarily, you can see how the return on investment in the long run for children’s health is really in the positive,” said Todd Florin, MD, MSCE, associate professor at Northwestern University Feinberg School of Medicine. The research team will collaborate with 12 pediatric care offices to gather data over the next five years.
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Long Covid continues to evade a clear diagnostic test, researchers reported in a study published Monday in the Annals of Internal Medicine. The findings are part of the National Institute of Health’s RECOVER Initiative, a billion-dollar-plus effort launched in 2021 to research causes and treatments for the estimated 17 million Americans with long Covid. Patients in the study were determined to have long Covid based on a scoring system of 12 symptoms including brain fog, dizziness and palpitations, among others. Different symptoms were assigned different scores, and a long Covid diagnosis was met if the score reached a level of 12. Marc Sala, MD, a pulmonologist and co-director of the Comprehensive Covid Center at Northwestern Medicine, said the study was well done but noted that the results might be frustrating to the millions out there still suffering from the illness. “I think one of the criticisms that can be leveled against the study is that a lot of these labs that they sent are the same things that you get with your primary care doctor,” Sala said. “A lot of these tests weren’t exactly nuanced to looking for a novel reason for long Covid.” Sala said that while routine blood tests are often normal with his long Covid patients, more specialized testing — such as blood tests while a patient is exercising, or a CT scan after Covid pneumonia — turns up abnormal. He said patients, particularly those who are otherwise healthy and come in with an extraordinary amount of shortness of breath and fatigue, would need much more testing beyond what was done in the paper.
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It is no mystery why rates of anxiety and depression in the United States climbed in 2020, at the height of the pandemic. But then life began a slow return to normal. Why haven’t rates of distress returned to normal, too? Researchers say a big reason for this stubbornly elevated distress is young people, whose low mood was not linked to the pandemic. The share of young adults reporting anxiety and depression had been rising for about a decade before Covid struck. That continued throughout the pandemic — and did not ease as quickly when vaccines became available. This is likely because their symptoms were tied to problems other than the virus, like economic precarity, the housing crisis, social isolation and political turmoil, said Emma Adam, PhD, a psychologist at Northwestern. “There’s so many things affecting adolescents and young adults that are about uncertainty with their future,” Adam said. “And that hasn’t changed.” Age, of course, tracks with income. Adam’s team found that people between the ages of 18 and 39 were half as likely to live in their own home as their counterparts over 40. That means they were especially vulnerable to inflation, rent increases and job loss — just as they faced big decisions like whether to have children or own a home.
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f you get enough back aches, someone will eventually tell you that’s where your body stores stress. If your stomach hurts, you’ll hear the same thing: Your emotions are trapped in your belly. But what does that mean? Is your anxiety about work or money really coursing through your body and nestling into your organs and limbs? In short, no. “We can and do manifest stress physically. There’s no question about it,” says Steven Tovian, PhD, a clinical professor of psychiatry and behavioral sciences at the Feinberg School of Medicine at Northwestern University. “But it’s not like there’s a stress reservoir to the left of our kidneys—and when it bubbles over or overflows, we’ve got problems. It’s not that kind of boiling-cauldron analogy.” Unfortunately, the truth is that stress lives everywhere inside your body. Here’s what really happens in your body when you’re stressed. The type of stress you’re dealing with—and its frequency, duration, and intensity—plays a role in determining how it might manifest in your body. There are a number of different types: acute (sitting in a traffic jam), episodic (work projects that pop up occasionally), chronic (losing a job, getting divorced, or dealing with a long-term illness), and traumatic (childhood abuse). “Stress is not one entity,” Tovian says. While acute stress, for example, is typically fleeting and can be resolved by calming regimens like deep breathing, leaving no lingering effects in its wake, other types of stress require more vigilance.
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Grandfather shares experience after awake kidney transplant surgery at Northwestern Medicine. Harry Stackhouse was diagnosed with COVID-19 in December 2019, which is when doctors noticed one of his kidneys was failing, and the other was only working at 2%, according to Northwestern. On July 15, Stackhouse underwent a surgery that took just under two hours. He said he did not feel anything and has been able to go on one-mile walks everyday since being discharged. Satish Nadig is the transplant surgeon and director of the Northwestern Medicine Comprehensive Transplant Center who performed Stackhouse’s transplant. “Patients who have cardiopulmonary disease may be at higher risk for general anesthesia,” Dr. Nadig said. “There are also some patients around the country who have had complications from their intubations in the past and do not want to be intubated. An awake kidney transplant procedure could be their best option.”
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A Zion man is the second to recover from an awake kidney transplant at Northwestern Medicine. Harry Stackhouse was diagnosed with COVID-19 in December 2019, which is when doctors noticed one of his kidneys was failing, and the other was only working at 2%, according to Northwestern. One of his daughters offered to donate her kidney to him. Stackhouse fit the criteria for what Northwestern Medicine is hoping to do as it establishes the Accelerated Surgery Without General Anesthesia in Kidney Transplantation program, also known as the AWAKE Kidney Program. Satish Nadig, MD, PhD is the transplant surgeon and director of the Northwestern Medicine Comprehensive Transplant Center who performed Stackhouse’s transplant. “Patients who have cardiopulmonary disease may be at higher risk for general anesthesia,” Dr. Nadig said. “There are also some patients around the country who have had complications from their intubations in the past and do not want to be intubated. An awake kidney transplant procedure could be their best option.”
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For many, driving long distances to receive cancer care is necessary. To get treatment, a woman must drive nearly three hours east to San Antonio, TX from her hometown of Del Rio, TX. For rural patients, getting cancer treatment close to home has always been difficult. But in recent years, chemotherapy deserts have expanded across the United States, with 382 rural hospitals halting services from 2014 to 2022, according to a report published this spring by Chartis, a health analytics and consulting firm. Loss of chemotherapy services can signal other gaps in cancer care, such as a shortage of local specialty physicians and nurses, which is bad news for patients, said Marquita Lewis-Thames, PhD, an assistant professor at Northwestern University in Chicago whose research covers rural cancer care. Rural patients are less likely to survive at least five years after a cancer diagnosis compared with their urban counterparts, concluded a study co-authored by Lewis-Thames and published in JAMA Network Open in 2022. While the rural-urban survival gap narrowed over the nearly 40 years researchers studied, the disparity persisted across most racial and ethnic groups, with only a few exceptions, she said.
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A newly developed biomaterial might be able to treat crippling arthritis by prompting the growth of new cartilage, a new animal study suggests. The biomaterial successfully regenerated high-quality cartilage in the knee joints of sheep within six months. “Cartilage is a critical component in our joints,” said lead researcher Samuel Stupp, PhD, a professor of materials science and engineering at Northwestern University. “When cartilage becomes damaged or breaks down over time, it can have a great impact on people’s overall health and mobility.” Further, Stupp explained, “The problem is that, in adult humans, cartilage does not have an inherent ability to heal,” Stupp added in a university news release. “Our new therapy can induce repair in a tissue that does not naturally regenerate. We think our treatment could help address a serious, unmet clinical need.” The new biomaterial combines an essential protein for cartilage growth and maintenance with a modified hyaluronic acid, which is naturally present in both cartilage and lubricating synovial fluid in joints.
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The term colorism — a form of prejudice and discrimination in which lighter skin is favored over darker skin — was popularized by author Alice Walker in her 1983 book “In Search of Our Mothers’ Gardens: Womanist Prose.” Clinicians from various ethnic groups have recently begun to draw a direct line between colorism and poor health. A 2023 KFF survey found that, among Black and Hispanic adults, those with self-described darker skin tones reported more experiences with discrimination in daily life compared with those who have lighter skin tones. People who feel like they experience daily discrimination can be at higher risk for depression, loneliness, increased alcohol and drug use, and anxiety, data shows. And colorism can also lead to physical health concerns. Hair straighteners and skin lighteners commonly used by women of color, sometimes to conform to racialized beauty standards, increase their exposure to toxic chemicals, research shows. The feeling of shame and embarrassment colorism produces in people is palpable and needs to be acknowledged in health care settings, said Roopal Kundu, MD, a dermatologist who founded and directs the Northwestern Medicine Center for Ethnic Skin and Hair in Chicago. Kundu, who is of South Asian heritage, opened the center in 2005 and notes that some cases of diseases like psoriasis, skin cancer, and eczema get diagnosed later, or misdiagnosed, because they present differently on diverse skin tones. “How can we really make sure, as a field, that we’re taking care of everybody?” she said. “Healthy skin is beautiful skin. And beauty is across every single skin tone that there is.”
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The suicide rate for U.S. children 8 to 12 years old has steadily climbed in the past decade and a half, with a disproportionate rise among girls, data released Tuesday by the National Institute of Mental Health shows. The findings, published in the journal JAMA Network Open, highlight pervasive issues regarding mental health that affect U.S. children daily, the study authors said. The coronavirus pandemic worsened the country’s ongoing mental health crisis, leading to increases in anxiety, depression and other mental health issues, according to experts. “This has been going on for a while, and we really saw things pick up when covid started [and] really seeing kids come in being miserable,” said Maria H. Rahmandar, MD, a pediatrician and co-author of the American Academy of Pediatrics clinical report on suicide and suicide risk in adolescents. “All of the pediatric providers I know were all hopeful that once kids were able to get back to school and their friends and a semblance of a normal life that mental health would improve, and we just haven’t seen that,” said Rahmandar, an associate professor at the Northwestern University Feinberg School of Medicine.