The work done by Northwestern University Feinberg School of Medicine faculty members (and even some students) is regularly highlighted in newspapers, online media outlets and more. Below you’ll find links to articles and videos of Feinberg in the news.
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For decades, it has been known that prostate specific antigen ‒ or PSA ‒ tests are a flawed way to diagnose prostate cancer. Many men have a high PSA without having cancer. Others have low PSA that might lead to aggressive tumors being missed in screenings. This has led to overtreatment of men who didn’t need biopsies or whose cancers would never have become dangerous and undertreatment of those whose tumors were missed. “The PSA is really the best blood cancer marker in all of medicine, but it’s not like a pregnancy test where everybody who’s positive is pregnant,” said Dr. William Catalona, a prostate cancer surgeon and professor of urology at Northwestern University’s Feinberg School of Medicine.
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Perhaps you’ve noticed how difficult it is just to see your doctor lately. It could take weeks, or even months. “People with disabilities are facing discrimination when they’re trying to make appointments with doctors,” said Tara Lagu, MD, MPH, of Northwestern University’s Feinberg School of Medicine, who has been studying this problem for several years in several studies. Lagu said it’s just a fact that, “nobody goes to medical school because they want to discriminate against vulnerable patients.” She further shared, “I remember how hard the system is to work in and how time-pressed doctors are,” she added. “The healthcare system is broken. I think for people with disabilities, it is the most extreme example.” Lagu also said many doctors are encouraged by insurance companies to keep visits short and see as many patients as possible in a day. She said that’s another problem, because people with disabilities often need more time than other patients.
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In 2015, the American Diabetes Association recommended Asian Americans get tested for diabetes at a body mass index of 23, lower than other groups. And they’ve worked from the inside to make their communities healthier. Dr. Namratha Kandula at Northwestern University started a diabetes prevention program for South Asians living near Chicago.
“And so what that means is in addition to talking about diet and exercise. We specifically address the stress that comes from being an ethnic minority in this country.”
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Suppose your young patient has a score indicating a heart attack is likely, perhaps a few decades or more later. If that patient starts taking a statin right away, as opposed to in midlife, will a heart attack be prevented? Dr. Sadiya Sana Khan of Northwestern University emphasized the need for more research. She has a new study showing that, in middle-aged to older adults, CT scans of the heart, which can show the buildup of plaque, are better than genetics in predicting risk. But that leaves a question about how to manage risk in young people, who almost never have visible plaque on a CT scan, even if they are at greater danger for a heart attack later in life. “We need more studies that focus on younger people with follow-up over several decades,” she said. If risk scores in young adults predict a greater likelihood of a heart attack, she asked, will that prediction be borne out when the people are older, at ages when heart attacks are more likely? Or will those with high risk scores instead be needlessly worried about their hearts?
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Researchers are one step closer to understanding why some babies are at greater risk of sudden infant death syndrome, or SIDS – the leading cause of death for infants one month to one year old. Most of the time, SIDS, sometimes called crib death, happens during sleep. One theory for SIDS is a disruption of a baby’s ability to breathe. A new study published in the Journal of Neuropathology & Experimental Neurology finds an abnormality in a brain receptor involved in the body’s protective response to gasp for air may play a role. In the 1990s, public health officials began promoting the “Back to Sleep” (now called “Safe to Sleep”) initiative to teach parents how to reduce SIDS risk by making sure babies sleep on their backs. Still, SIDS rates have “plateaued,” said Debra Weese-Mayer, Northwestern University professor of pediatric autonomic medicine, highlighting the importance of continued research, education and outreach.
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Xylazine isn’t an opioid, it’s a sedative, said Lindsay Allen, professor of emergency medicine at Northwestern University’s Feinberg School of Medicine. It is part of a class of adulterants, or cutting agents, but it looks and feels like an opioid when you’re taking it. “That’s what drug creators are counting on, because it’s a lot less expensive for them to add xylazine, or to cut their drugs with xylazine,” Allen said.
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“This is intriguing,” says Dr. Jeffrey Linder, chief of general internal medicine at Northwestern University Feinberg School of Medicine, who was not involved in the study. But he says the overall effect found in the study was quite small. “It seems like a pretty modest difference,” Linder says. And he points out that the multivitamins had no effect on other areas of cognition evaluated in the study, such as executive function, which may be more important measures.
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“[Young children’s] brains are craving sound-to-meaning connections, so it’s very important that the sounds around them be nourishing and meaningful,” says Nina Kraus, a neurobiologist at Northwestern University.
She believes turning down the noise in our lives starts with embracing — even enjoying — silence.
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After two months of tests, a mom of three was diagnosed with amyotrophic lateral sclerosis or ALS, also known as Lou Gehrig’s disease. ALS impacts the nerves that control our muscles, causing them to weaken and atrophy. There’s no cure. “It was devastating to realize that our plans for our young family were completely upended by my diagnosis,” Rankin said. Dr. John Coleman, a critical care pulmonologist at Northwestern Medicine and a member of Rankin’s extensive care team, says Rankin is not alone. “I think she is a testament of the younger generation of people who have ALS. ALS has always been kind of thought about as a disease that has affected older people, maybe in their 60s or 70s, but we’re seeing more and more young people being diagnosed with ALS,” Coleman said.
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Sometimes it may seem as if half the population of the United States takes medication for high cholesterol levels. About 40 million Americans are taking statins such as atorvastatin (Lipitor and generic), lovastatin (Altoprev) and simvastatin (Zocor), which are by far the most commonly prescribed of all types of cholesterol drugs. Statins can be quite effective. Donald Lloyd-Jones, MD, shares advice on how to lower cholesterol. Regular consumption of unsaturated fats (olive oil, avocados, nuts, seeds) and soluble fiber (oats, barley, psyllium) may lower LDL cholesterol by about 7 to 15 mg/dL. Limit full-fat dairy, red meat and fried food because their saturated fat can raise LDL, says Donald Lloyd-Jones, chair of preventive medicine at the Northwestern University Feinberg School of Medicine in Chicago.