Category: Scientific Advances
-
Bone Transcription Factor Controls Nervous System Gene Expression
An established transcription factor known for bone formation also supports specialized cells in the central nervous system to promote brain tissue stiffness, findings that could inform new therapeutics for neuronal regeneration, according to a Northwestern Medicine study published in Neuron.
-
Evolving Telehealth Research and its Place in Healthcare Delivery
Since the COVID-19 pandemic thrust many providers into telehealth appointments, scientists have been asking questions about the benefits and concerns of telehealth. While telehealth was in use and gathering interest prior to the pandemic, the need for it accelerated during a time when people were encouraged to stay home.
-
New Human Gene Cluster Sequence Discovered
Investigators from the laboratory of Ali Shilatifard, PhD, have discovered a new repeat gene cluster sequence that is exclusively expressed in humans and non-human primates, according to findings published in Science Advances.
-
Pioneering Automated Proteoform Imaging
Investigators led by Neil Kelleher, PhD, have developed an automated technique for imaging proteoforms in ovarian cancer, according to results published in Nature Communications.
-
Developing Custom AI Language Models to Interpret Chest X-Rays
Northwestern Medicine scientists have developed an artificial intelligence (AI) tool able to interpret chest X-rays with accuracy rivalling that of a human radiologist, according to findings published in JAMA Network Open.
-
Exploring Transcription Elongation Control in Development, Disease and Aging
In a recent article published in Molecular Cell, the laboratory of Ali Shilatifard, PhD, provided a comprehensive overview of the current understanding of the elongation stage of DNA transcription and how its dysregulation is associated with developmental defects, disease and aging.
-
Identifying Molecular Culprits Underlying Organ Rejection
Investigators have identified how bacterial infection can alter immune response to precipitate organ rejection in mice, findings which may prove useful for improving transplant tolerance in humans, according to a recent study published in the Journal of Clinical Investigation.
-
Study Discovers New Subset of Retinal Neurons Impacting Vision
Investigators have discovered a new subtype of interneurons in the retina that allows the eye to see and identify objects better in both the light and in the dark, dismantling previous notions about the inner workings of the retina, according to a Northwestern Medicine study.
-
Visual Abstracts in Journal Articles Increase Social Media Engagement, Readership
Social media posts with visual abstracts — images with text and icons that convey a study’s methods and findings — of clinical trials published online in peer-reviewed academic journals increased social media engagement compared to social media posts with article figures, according to a recent research letter published in JAMA.
-
Understanding How Sex-Based Differences Impact Health Outcomes
Sex is a major determinant in disease prevalence and treatment response, caused by a vast number of genetic differences between men and women. However, the inclusion of both sexes in clinical and scientific research had not been mandated by federal law until nearly the turn of the century.
