Category: Scientific Advances
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Uncovering the Genetic Mechanisms Driving Embryonic Development
A new Northwestern Medicine study, published in Genes and Development, has identified two DNA elements crucial to the activation of a set of genes that drive the early development of embryos.
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Uncovering a Novel Mechanism in Cell Division
Northwestern Medicine scientists have demonstrated an important role for the methylation of the amino terminus of a specific protein in maintaining centromere function and chromosome segregation, both important in cell division.
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Identifying a Novel Target for Cancer Immunotherapy
Targeting a molecule called B7-H4 may lead to the development of new therapies that boost the immune system’s ability to fight cancer, according to a review published in the journal Immunological Reviews.
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Scientists Develop Novel Platform to Investigate Therapeutic Nanomaterials
Northwestern Medicine scientists have developed a novel testing platform to assess, in real time, the efficacy of nanomaterials in regulating gene expression.
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New Insights Into Sodium Channel Structure
Northwestern Medicine scientists have mapped the complete structure of a voltage-gated sodium channel, proteins in the membrane of cells that play an important role in many diseases.
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New Insights into the Regulation of Cellular Iron
Northwestern Medicine scientists have uncovered a novel pathway in the regulation of cellular iron, findings that were published in the Journal of Clinical Investigation.
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Unexpected Role for Calcium Ion Channel Protein Revealed
Northwestern Medicine scientists and collaborators have shown that a protein thought to form calcium ion channels instead regulates the activity of another member of the family to modulate immune responses.
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Insights Into the Essential Building Blocks of the Nucleus
A new study defined the architecture of nuclear lamins, the fibrous proteins in a cell’s nucleus, providing further insights into their role in cell structure.
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A Universal Solution for Regenerative Medicine
Revolutionary nanomaterials developed at Northwestern could make it possible to repair tissues and organs spanning from bone and cartilage to muscle and brain tissues.
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Understanding How Calcium Channels Open and Close
Northwestern Medicine scientists identified the process by which a calcium channel called the CRAC channel opens and closes, and how mutations in the channel structures that control its opening cause disease.
