Category: Scientific Advances
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Study Uncovers Novel Synaptic Intricacies Inside the Retina
A Northwestern Medicine study has uncovered novel cellular mechanisms within the retina, findings that could help advance the development of targeted therapeutics for diseases and conditions impacting vision.
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Study Identifies Novel Regulators of Hippocampal Overactivity
Reduced expression of specific calcium channels impaired electrical signaling between neurons and contributed to the onset of behaviors associated with neurodevelopmental disorders and seizure susceptibility in mouse models, according to a Northwestern Medicine study.
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Study Identifies New Mechanisms Driving Genomic Instability
A recent Northwestern Medicine study has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of biomarkers and targeted therapies for cancer.
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Improving Cancer Detection for Women with Dense Breasts
The use of ultrasound screening and 3D mammography only slightly increases the detection rate of breast cancer in women with dense breasts, according to a prospective multicenter study published in the Journal of Clinical Oncology.
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Study Establishes Fluctuating ’Gating’ Mechanisms Supporting Flexible Behavior
A study led by Elizabeth Johnson, PhD, has established fluctuating “gating” mechanisms that support flexible behavior and working memory in humans, findings recently published in Nature Communications.
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Understanding How Hormones Influence Anemia
Northwestern Medicine scientists have uncovered how peptides produced by bones during inflammation prevent anemia in mice, according to a recent study published in the journal Blood.
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Improving the Study of Sex-Based Differences in Complex Traits and Disease
Investigators led by Barbara Stranger, PhD, associate professor of Pharmacology, developed a guide outlining best practices for studying and testing sex-dependent genetic effects in complex traits and diseases, published in the journal Cell.
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Improving Crystal Engineering with DNA
Northwestern investigators have demonstrated that fine-tuning DNA interaction strength can improve colloidal crystal engineering to enhance their use in creating an array of functional nanomaterials.
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NIH Toolbox App Provides Access to Tests for Cognition, Motor, Sensation and Emotion
An iPad app developed by Northwestern Medicine investigators that helps measure specific aspects of cognitive, motor, sensory and emotional function in five minutes or less is now available for doctors to screen people ages 3 to 85+ for a wide range of neurological diseases and syndromes.
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Understanding the Role of Octopamine in Neurodegeneration
Northwestern Medicine scientists have discovered how octopamine, the major “fight-or-flight” neurotransmitter in invertebrates, communicates with other cells to prevent cell death in mammalian brains, according to a study published in the Proceedings of the National Academy of Sciences.
