Category: Disease Discoveries
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New Genes Implicated in Uterine Fibroid Development
Northwestern Medicine scientists have identified new genes implicated in the development of uterine fibroids, according to a study published in Nature Communications.
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Release of Inhibitory Pathways May Promote Immune Response to HIV
Recent work from the laboratory of Elena Martinelli, PhD, MPH, has discovered how inhibiting an immune cell singling pathway in a model of HIV-1 infection may promote immune responses and decrease viral persistence in conjunction with antiretroviral therapy.
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Innate Immune Cells Promote Growth of Blood Vessels in Colon Cancer
A type of white blood cell is responsible for growth and branching of blood vessels which supports tumor growth in colon cancer, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.
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Outsmarting Chemo-Resistant Ovarian Cancer
Northwestern Medicine scientists have discovered the Achilles heel of chemotherapy-resistant ovarian cancer — its hunger for cholesterol — and how to sneakily use that to destroy it.
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Genes May Predict Treatment Resistance in Prostate Cancer
Increased expression of specific genes in prostate cancer patients may predict whether or not the cancer will respond well to hormone therapy, according to a new study published in Nature Communications.
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Immune Genes Are Altered in Alzheimer’s Patients’ Blood
A new study has found the immune system in the blood of Alzheimer’s patients is epigenetically altered, and many of these altered genes are the same ones that increase an individual’s risk for Alzheimer’s.
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Using Cancer’s Strength to Fight Against It
In findings published in Nature, scientists may have found a way around the limitations of engineered T-cells by borrowing a few tricks from cancer itself.
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Study Identifies Molecular Mechanisms of Rare Neurodevelopmental Disorder
Investigators from the laboratory of Alicia Guemez-Gamboa, PhD, assistant professor of Neuroscience, have discovered new molecular mechanisms of PACS1 syndrome, a rare neurodevelopmental disorder, according to findings published in Nature Communications.
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Decorated Nanoparticles Prevent Allergic Reactions
Northwestern University scientists have developed the first selective nanoparticle therapy to prevent allergic reactions, which can range in severity from itchy hives and watery eyes to trouble breathing and even death.
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New Cause of Neuron Death in Alzheimer’s Discovered
A new Northwestern Medicine study has identified short strands of toxic RNAs that contribute to brain cell death and DNA damage in Alzheimer’s and aged brains.
