Category: Disease Discoveries
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Stopping Tumor Growth During Hypoxia
Inhibiting a ubiquitin ligase stops tumor growth during hypoxia, a common characteristic of lung and brain cancers.
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New Understanding of Cystic Fibrosis Gene Expression
Nehal Gosalia, ’14 PhD, examined the role of architectural proteins in regulation of expression of the cystic fibrosis gene.
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Detecting Early Stage Knee Osteoarthritis
Northwestern Medicine scientists found that lesions seen in MRIs of knees without any x-ray signs of osteoarthritis predict the development of persistent symptoms of the disease and the first appearance of cartilage damage.
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A New Way to Prevent Organ Transplant Rejection
Northwestern Medicine scientists discovered a method to promote organ transplant tolerance by limiting the immune response in a novel way.
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Scientists Develop First Animal Model for ALS Dementia
Northwestern Medicine scientists have developed the first animal model for ALS dementia, a form of ALS that also damages the brain, allowing for direct monitoring of test drugs to determine if they work.
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First Blood Test to Diagnose Depression in Adults
Northwestern Medicine scientists developed the first blood test to diagnose major depression in adults and to predict who will benefit from cognitive behavioral therapy.
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Pathway Found for Treating Fatal Lung Disease
Northwestern Medicine scientists identified genes correlated with the progression and severity of idiopathic pulmonary fibrosis.
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New Insights for Therapeutic Intervention in Melanoma
Mary J.C. Hendrix, PhD, revealed a variance in signaling pathways in embryonic stem cells and metastatic melanoma cells that may impact new therapeutic strategies in cancer.
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Stress Increases Women’s Chance of Cardiovascular Disease
A study analyzed data from 82,000 women to see how stressful life events and social strain affect future development of coronary heart disease and stroke.
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Scientists Developing Eye Drops to Treat Blindness
Northwestern Medicine scientists have discovered a novel cause of glaucoma in an animal model, and related to their findings, are now developing an eye drop aimed at curing the disease.
