Category: Disease Discoveries
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Decoding Signaling Pathways that Lead to Scar Tissue
The loss of a component of a protein complex responsible for attaching cells together activates genes that lead to the buildup of fibrous scar tissue seen in cardiac disease arrhythmogenic cardiomyopathy, according to a recent study.
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Rescuing Damaged Neurons in Parkinson’s Disease
Northwestern Medicine scientists shed light on a hallmark of Parkinson’s disease that has been poorly understood, the buildup of a protein called α-synuclein in the brain.
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Nanoparticles Destroy Cancer With Mechanical Force
By rotating special magnetic nanoparticles injected into brain tumors, a team of scientists led by Northwestern Medicine neurosurgical oncologist Maciej (Matt) Lesniak, MD, successfully damaged tumor cells in animal models.
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HIV Is Still Growing, Even When Undetectable In The Blood
HIV still replicates in lymphoid tissue, even when it is undetectable in the blood of patients on antiretroviral drugs, according to new Northwestern Medicine research.
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Targeting Upper Motor Neurons to Treat ALS
Scientists showed that it is possible to specifically modify gene expression in diseased upper motor neurons in a new Northwestern Medicine translational study.
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Graduate Student Investigates Control Mechanisms for the Cystic Fibrosis Gene
Rui Yang, a graduate student in the Driskill Graduate Program, studied the chromatin structure and expression of the gene that, when mutated, causes cystic fibrosis.
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Mutation Unique to Childhood Kidney Cancer Discovered
A recent study led by Elizabeth Perlman, MD, discovered a new genetic mutation in the most common type of pediatric kidney cancer, Wilms tumor.
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Targeting Immunosuppression in Brain Tumors
Research conducted in the laboratory of Derek Wainwright, PhD, assistant professor of Neurological Surgery, explores strategies to reverse pathways that inhibit the body’s immune system from fighting glioblastoma.
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Accelerating Prostate Cancer Research
Northwestern Medicine scientists have received a five-year, $11 million grant from the National Institutes of Health National Cancer Institute (NCI) to lead a Specialized Program of Research Excellence (SPORE) in prostate cancer.
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Ending Chronic Pain With New Drug Therapy
A brain region controlling whether we feel happy or sad, as well as addiction, is remodeled by chronic pain, according to a new Northwestern Medicine study, and a new treatment targeting this region may dramatically lessen symptoms.
