Category: Disease Discoveries
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Brain Rewiring in Parkinson’s Disease May Contribute to Abnormal Movement
A study published in Neuron suggests the brain’s own compensatory mechanisms contribute to the debilitating motor symptoms of Parkinson’s disease.
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Genomic Analysis Offers Insights into Cause of Wilms Tumor
A comprehensive genomic analysis of the most common kidney cancer in children – found genetic mutations involving two distinct processes, potentially providing new opportunities for future treatments.
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Scientists Discover Key Cellular Mechanism Underlying Parkinson’s Disease
The major features of Parkinson’s disease have been linked to a toxic cascade beginning with oxidized dopamine, providing a possible therapeutic pathway.
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Novel Approach Offers New Insights Into HIV’s Lifecycle
Northwestern Medicine scientists have developed a novel method of tracking HIV infection, allowing the behavior of individual virions to be connected to infectivity.
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Scientists Identify Mutations in Venous Valve Disease
Mutations in the genes FOXC2 and GJC2 are associated with defects in venous valves, according to a new study published in the Journal of Experimental Medicine.
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Genetic Risk for Lupus Tied to Ancestry
A Northwestern Medicine study analyzing the genomes of more than 27,000 individuals has uncovered that ethnic disparities in lupus diagnoses have a genetic basis.
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Novel Screening Method Reveals Glioblastoma Drug Target
Scientists used a new approach to identify a promising therapeutic target for glioblastoma, which was previously overlooked in traditional approaches.
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Nanomedicine Opens Door to Precision Medicine for Brain Tumors
Early phase Northwestern Medicine research has demonstrated a potential new therapeutic strategy for treating glioblastoma.
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Root of Cardiac Fibrosis Defined
Northwestern Medicine scientists identified a novel molecular mechanism that regulates scar formation in the heart, a symptom of aging and heart disease.
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PhD Student Explores Enzyme’s Role in Aggressive Brain Tumor
Northwestern Medicine scientists have demonstrated that an enzyme called IDH1 plays a significant role in cancer progression and may be a target for novel drug therapies.
