Category: Disease Discoveries
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Brain Lesion Location Influences Addiction Behaviors
Damage to particular regions of the brain may influence addiction behaviors, providing insight into potential therapeutic targets for substance use disorders.
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Targeting Bicarbonate in Cancer
Bicarbonate ions are required for cell growth in some cancers, according to a Northwestern Medicine study.
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Anti-seizure Medication has a New Target
Designed to target AMPAR receptors in the brain, the medication — called perampanel — also modulates kainate receptors.
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Epigenetic Biomarkers Predict CVD Risk
A new study provides evidence that blood epigenetic biomarkers contain “snapshots” of past cardiovascular health exposures and behavior at the molecular level.
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Deep-learning Empowers Discovery of New Genetic Mutation in Cancer
A deep learning model has discovered genetic variations in cancer that are undetectable in traditional genome sequencing.
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Northwestern Investigates COVID-19: Omicron, Vaccines, Pediatric Complications
Northwestern Medicine investigators have continued to examine COVID-19, from the impact of prone positioning during treatment to vaccine protection against the Omicron variant in children.
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Genetic Variants in Epilepsy Gene Identified
Investigators have discovered a new method to determine whether individual genetic variants in the epilepsy-associated gene SZT2 cause the neurodevelopmental disorder, according to a Northwestern Medicine study.
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Genome-wide Intricacies of Cancer Inhibitor Untangled
A newly discovered inhibitor of a common cancer-causing protein operates selectively, reducing expression of genes that fuel rampant cell proliferation, and altering the epigenome, according to a recent study.
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Study Shows Cell Membrane-Bound Enzyme is Essential for COVID-19 Infection
The membrane-bound form of the ACE2 protein is the essential receptor for enabling COVID-19 infectivity, according to a Northwestern Medicine study.
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Study Identifies New Therapeutic Target for Most Common Type of Pancreatic Cancer
Northwestern Medicine investigators have discovered a potential therapeutic target for the most common type of pancreatic cancer, according to a study published in Developmental Cell.
