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Category: Clinical Breakthroughs

  • Study Identifies Disparities in End-of-Life Care for Lung Cancer Patients

    Study Identifies Disparities in End-of-Life Care for Lung Cancer Patients

    Patients with lung cancer who were Asian/Pacific Islander, Black or Hispanic experienced a higher intensity of end-of-life care compared to white patients, according to a Northwestern Medicine population-based analysis published in the Journal of Clinical Oncology.

  • Drug Shows Promise for Starving Out Cancer Cells

    Drug Shows Promise for Starving Out Cancer Cells

    Starving out tumor cells may be a promising therapy for treatment-resistant lung cancer, according to a study published in Science Advances.

  • Skin Patch Improves Treatment for Pediatric Milk Allergies

    Skin Patch Improves Treatment for Pediatric Milk Allergies

    Daily immunotherapy delivered via a dermal patch reduced risk of reactions, including anaphylaxis, in children with an immunoglobulin E (IgE)–mediated cow’s milk allergy, according to a recent clinical trial published in JAMA Pediatrics.

  • Dietary Supplements Can Reduce Cancer Mortality but May Increase Cardiovascular Mortality

    Dietary Supplements Can Reduce Cancer Mortality but May Increase Cardiovascular Mortality

    Postmenopausal women who took calcium and vitamin D supplements demonstrated reduced cancer mortality but increased cardiovascular mortality after a 20-year follow-up period, according to post-hoc analysis results published in Annals of Internal Medicine.

  • Targeting Protein Interactions May Boost Antitumor Immunity in Breast Cancer

    Targeting Protein Interactions May Boost Antitumor Immunity in Breast Cancer

    A multi-institutional team of investigators has discovered that targeting a specific protein interaction within immunosuppressive breast cancer cells may increase antitumor immune responses, according to findings published in the Journal of Clinical Investigation.

  • MRI Surveillance Significantly Reduces Breast Cancer Mortality 

    MRI Surveillance Significantly Reduces Breast Cancer Mortality 

    Women with breast cancer who carried the BRCA1 breast cancer mutation and who were enrolled in an MRI surveillance program saw an 80 percent reduction in breast cancer mortality compared to those who did not undergo MRI surveillance, according to findings published in JAMA Oncology.

  • Setting International Standards for Diagnosing Pediatric Sepsis

    Setting International Standards for Diagnosing Pediatric Sepsis

    A large international team led by a Northwestern Medicine investigator has established new standardized diagnostic criteria for pediatric sepsis, according to two related studies published in JAMA.

  • Deploying Polygenic Risk Scores in Primary Care Settings

    Deploying Polygenic Risk Scores in Primary Care Settings

    A multi-institutional team of investigators have developed a new framework for supporting healthcare providers in implementing polygenic risk score-based testing into primary care settings, according to a recent study published in Nature Medicine.

  • ‘Polypills’ Can Help Patients Reduce Heart Disease Risk

    ‘Polypills’ Can Help Patients Reduce Heart Disease Risk

    Combining multiple heart disease drugs into a single “polypill” can lower bad cholesterol and blood pressure, boost medication adherence, and reduce the risk of cardiovascular disease and death, according to a meta-analysis of recent clinical trials published in Nature Medicine.