Category: Clinical Breakthroughs
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First Drug to Reduce Risk of Mortality and Hospitalization in Heart Failure
Dapagliflozin, a sodium-glucose cotransporter 2 inhibitor, reduced the risk of cardiovascular-related morality and hospitalization in patients with heart failure, regardless of ejection fraction, according to a series of clinical trial reports.
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Study Finds Biologic Drug ‘Highly Effective’ in Reducing Pediatric Eczema Symptoms
The first biologic drug to treat moderate-to-severe eczema in infants and children was highly effective in reducing symptoms, according to a recent study.
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Improving Drug Therapy for Relapsed Leukemia
A two-drug combination has been shown to improve patient response to treatment in relapsed or refractory acute myeloid leukemia.
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Survivors of Childhood Cancer Still at Risk for Infection Years After Diagnosis
After a pediatric cancer diagnosis, chances of infections remain elevated for more than a decade, according to a recent study.
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Leading Translational Gastroenterology Research
Northwestern Memorial Hospital was recently ranked seventh in the country for Gastroenterology & Gastrointestinal (GI) surgery by US News and World Report. This article was originally published in August 2022 Breakthroughs.
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Investigating the Utility of Polygenic Risk Scores for CHD
Polygenic risk scores demonstrated minimal clinical benefit in predicting long-term coronary heart disease when added to a traditional risk factor model, according to a Northwestern Medicine study.
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Northwestern Awarded First-Ever National Grant to Study Wearables, Stroke Prevention in Patients With Atrial Fibrillation
Northwestern University has been awarded a seven-year grant to study a “pill-in-pocket” strategy to prevent stroke in patients with atrial fibrillation, the most common heart rhythm disorder in adults.
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Coming Wave of Opioid Overdoses ‘Will be Worse Than Ever Been Before’
Geography played a role in opioid-involved overdose deaths in the past, but a coming wave may discriminate between rural and urban areas, according to a recent study.
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Diabetes Drug Metformin Shows Potential Benefit in Large COVID-19 Trial
Metformin, a common, safe and inexpensive drug for type 2 diabetes, lowered the odds of emergency department visits, hospitalizations or death due to COVID-19 by over 40 percent, according to a new multi-site clinical trial.
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Novel Telehealth Strategy Will Treat Three Cancer Risk Behaviors at Once
A new Northwestern Medicine trial will test whether a telehealth-based intervention that addresses three behavioral risk factors at once can modify cancer patients’ lifestyles to improve their outcomes.
