Byline: Michelle Mohney
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Award Funds International Vascular Malformation Research
An international collaboration for which Luisa Iruela-Arispe, PhD, chair of Cell and Developmental Biology, serves as North American coordinator, has received a five-year, $7 million Transatlantic Networks of Excellence Program award from the Leducq Foundation.
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Bioinformatic Computational Tool Analyzes Tissue Samples to Discern Disease
A novel integrative computational technique allowed scientists to classify disease conditions at the molecular level using epigenomic data sets.
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Uncovering the Impact of Protein Mutations in Parkinson’s
Northwestern scientists have determined how two protein mutations responsible for the impaired motor function in Parkinson’s disease independently disrupt neuron activity.
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‘Cluster Bomb’ Toxin from Cholera Shuts Down Inflammatory Response While Attacking Cells
Northwestern scientists have determined that a toxin secreted by Vibrio cholerae bacteria, the pathogen responsible for cholera, suppresses the body’s normal immune response.
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New Approach Shows Promise in Treating Parkinson’s Symptoms
Northwestern Medicine scientists have rescued movement in a mouse model of Parkinson’s disease by restoring the intrinsic discharge of nerve cells within the subthalamic nucleus.
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Exploring the Molecular Mechanisms of Ion Channels and Kidney Disease
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
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Calcium Channels Play Essential Role in Astrocyte Activity
Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
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Mitochondria Linked to Autoimmunity
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
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Delayed Development of Fast-Spiking Neurons Linked to Fragile X
Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a neurodevelopmental disorder.
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Poxvirus Yields New Insights into Protein Synthesis
Northwestern Medicine scientists studied a poxvirus and demonstrated that ribosomes can selectively control the process of protein synthesis known as translation.
