New Approach Shows Promise in Treating Parkinson’s Symptoms
Northwestern Medicine scientists have rescued movement in a mouse model of Parkinson’s disease by restoring the intrinsic discharge of nerve cells within the subthalamic nucleus.
Browsing: Michelle Mohney
Exploring the Molecular Mechanisms of Ion Channels and Kidney Disease
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
Calcium Channels Play Essential Role in Astrocyte Activity
Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
Mitochondria Linked to Autoimmunity
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
Delayed Development of Fast-Spiking Neurons Linked to Fragile X
Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a neurodevelopmental disorder.
Poxvirus Yields New Insights into Protein Synthesis
Northwestern Medicine scientists studied a poxvirus and demonstrated that ribosomes can selectively control the process of protein synthesis known as translation.
Huntington’s Disease Linked to Dysfunction of Brain Structure
Northwestern Medicine scientists have identified a link between Huntington’s disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.
Satchell, Shilatifard Elected AAAS Fellows
Ali Shilatifard, PhD, Robert Francis Furchgott Professor and Chair of Biochemistry and Molecular Genetics, and Karla Satchell, PhD, professor of Microbiology-Immunology, have been elected as 2016 fellows of the American Association for the Advancement of Science (AAAS).
Transcription Factor Responsible for Variability in Congenital Brain Disorder
Northwestern Medicine scientists have identified one of the molecular mechanisms behind the variability of holoprosencephaly, a congenital brain malformation.
Enzyme Identified as Target Against Triple-Negative Breast Cancer
Northwestern Medicine scientists identified an enzyme as a potential new target for triple-negative breast cancer, a form of breast cancer that is associated with early tumor recurrence and significantly increased mortality rates.