Northwestern scientists have determined that a toxin secreted by Vibrio cholerae bacteria, the pathogen responsible for cholera, suppresses the body’s normal immune response.
Northwestern Medicine scientists have rescued movement in a mouse model of Parkinson’s disease by restoring the intrinsic discharge of nerve cells within the subthalamic nucleus.
Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a neurodevelopmental disorder.
Northwestern Medicine scientists studied a poxvirus and demonstrated that ribosomes can selectively control the process of protein synthesis known as translation.
Northwestern Medicine scientists have identified a link between Huntington’s disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.
Ali Shilatifard, PhD, Robert Francis Furchgott Professor and Chair of Biochemistry and Molecular Genetics, and Karla Satchell, PhD, professor of Microbiology-Immunology, have been elected as 2016 fellows of the American Association for the Advancement of Science (AAAS).
Northwestern Medicine scientists have identified one of the molecular mechanisms behind the variability of holoprosencephaly, a congenital brain malformation.