Northwestern Medicine scientists have discovered the molecular mechanism by which voltage-dependent gates regulate the flow of ions in a unique sub-class of proteins called polycystic receptor potential channels.
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Northwestern Medicine scientists have identified the critical role that a specific ion channel plays in the activity of brain cells called astrocytes.
Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.
Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a neurodevelopmental disorder.
Northwestern Medicine scientists studied a poxvirus and demonstrated that ribosomes can selectively control the process of protein synthesis known as translation.
Northwestern Medicine scientists have identified a link between Huntington’s disease and dysfunction of the subthalamic nucleus, a component of the basal ganglia, a group of brain structures critical for movement and impulse control.
Ali Shilatifard, PhD, Robert Francis Furchgott Professor and Chair of Biochemistry and Molecular Genetics, and Karla Satchell, PhD, professor of Microbiology-Immunology, have been elected as 2016 fellows of the American Association for the Advancement of Science (AAAS).
Northwestern Medicine scientists have identified one of the molecular mechanisms behind the variability of holoprosencephaly, a congenital brain malformation.
Northwestern Medicine scientists identified an enzyme as a potential new target for triple-negative breast cancer, a form of breast cancer that is associated with early tumor recurrence and significantly increased mortality rates.
Northwestern Medicine scientists have discovered that the cholera strain responsible for the 2010 epidemic in Haiti is a hypervirulent variant.