Byline: Melissa Rohman
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Study Finds Almost One-Third of U.S. Pediatric Inpatient Units Closed in Last Decade
From 2008 to 2022, U.S. hospitals closed nearly 30 percent of pediatric inpatient units but only 4.4 percent of adult inpatient units, according to a recent Northwestern Medicine analysis published in JAMA Pediatrics.
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Long-Lived Proteins Impact Aging of Female Reproductive System
For the first time, Northwestern Medicine scientists have identified a population of long-lived proteins in the ovaries which likely support the stability and longevity of the female reproductive system and may contribute to reproductive aging, according to a recent study.
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Improving the Treatment of Valvular Heart Diseases
Transcatheter heart valve replacement significantly improved outcomes in patients with severe valvular heart diseases compared to standard care alone, according to two recent clinical trials published in the New England Journal of Medicine.
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Improving Diagnosis and Tracking of Neurodegenerative Diseases
Investigators led by Tanya Simuni, MD, have defined new biologic and clinical biomarkers for better identifying patients with different stages of Parkinson’s disease and Lewy body dementia according to a recent study.
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Medical School Establishes Center for Computational and Social Sciences in Health
Northwestern University Feinberg School of Medicine has established the Center for Computational and Social Sciences in Health (COMPASS), which aims to foster connection and bridge data science, social science and population health.
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Combination Therapy Does Not Extend Survival in Glioblastoma
Patients with a subtype of glioblastoma who received a combination treatment of a PARP inhibitor and standard chemotherapy did not demonstrate improved survival compared to chemotherapy and placebo, according to a recent clinical trial published in JAMA Oncology.
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Improving Atopic Dermatitis Treatment for Adolescents
Long-term treatment with the drug upadacitinib significantly improved symptoms and quality of life compared to placebo in adolescents with moderate to severe atopic dermatitis after 76 weeks with strong evidence of safety, according to a recent Northwestern Medicine analysis of three international, randomized clinical trials.
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Thrombectomy Does Not Improve Outcomes for Patients with Large Strokes
Treatment with endovascular thrombectomy did not significantly improve outcomes after 90 days in patients with a large core stroke, as compared to patients who received standard stroke care alone, according to a recent clinical trial published in JAMA.
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Delayed Antibody Treatment May Improve Efficacy of mRNA Vaccines
Investigators led by Pablo Penaloza-MacMaster, PhD, associate professor of Microbiology-Immunology, have discovered that administering an antibody treatment four days after mRNA vaccination significantly improved vaccine efficacy in mice, according to findings published in The Journal of Clinical Investigation.
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Study Identifies Potential Therapeutic Target for PTSD
Targeting a specific neural circuit through noninvasive neuromodulation may reduce symptoms in patients with posttraumatic stress disorder (PTSD), according to a recent study published in Nature Neuroscience.
