Author: Olivia Dimmer
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Neighborhood Social Factors Increase Cardiovascular Disease Risk
Individuals exposed to adverse neighborhood social factors in early adulthood demonstrated a higher risk of developing coronary artery calcification in midlife, a key measure of early cardiovascular disease, according to a recent study published in Nature Communications.
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Cells ‘Switch’ on Protein Factories After Injury, Study Finds
Scientists have uncovered a novel mechanism through which skin cells organize and control protein production during homeostasis and wound healing, according to a new study published in Developmental Cell.
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Epilepsy Gene Implicated in Severe Migraine Disorder
Northwestern Medicine scientists have identified mutations in a gene coding for key ion channels in the brain as a new cause of a debilitating form of migraine, according to a study published in Brain.
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Understanding Cancer’s Hidden Vulnerabilities
Northwestern Medicine scientists have uncovered an unexpected role for a well-known cancer-related protein, revealing a new layer of genetic regulation that could reshape how certain cancers are treated.
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Long Non-Coding RNA May be a Promising Therapeutic Target for Cancer
Northwestern Medicine scientists have discovered that a specific long non-coding RNA activates oncogenic signaling pathways in prostate cancer cells and drives tumor progression, underscoring its potential as a therapeutic target, according to a recent study published in Nature Communications.
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Experimental Drug Lowers Parkinson’s-Linked Protein in Early Trial
An experimental drug designed to silence a gene strongly linked to Parkinson’s disease has shown encouraging effects in a first-in-human clinical trial, according to a study published in Nature Medicine.
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Overlooked Cells Linked to Poor Outcomes in Breast Cancer
A little-studied group of cancer cells circulating in the bloodstream may play a bigger role in breast cancer progression than previously thought, according to new research published in Science Translational Medicine that sheds light on how the disease spreads and why some patients fare worse than others.
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Uncovering a Genetic Driver of Rare Early-Onset Dementia
A global team of scientists has uncovered a new genetic risk factor for a rare and aggressive form of early-onset dementia, according to a study published in Nature Genetics.
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Study Identifies New Molecular Mechanisms Supporting Cell Adhesion
Scientists led by Sergey Troyanovsky, PhD, professor of Dermatology and of Cell and Developmental Biology, have uncovered new intracellular mechanisms promoting cell-cell adhesion, a process disrupted in a variety of skin and inflammatory diseases, according to a recent study published in the Journal of Cell Biology.
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Understanding Mechanisms of Rare Inflammatory Autoantibodies
Northwestern Medicine investigators have uncovered a missing link behind the harmful effects of autoantibodies linked to blood clots, pregnancy complications and other inflammatory conditions, according to a new study published in the Proceedings of the National Academy of Sciences.
