Author: Olivia Dimmer
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Targeting Key Proteins in Fight Against ALS
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein accumulation in neurodegenerative diseases, according to a study published in Nature Communications.
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How Inflammation Fuels Blood Cancer Risk
A Northwestern Medicine-led study published in The Journal of Clinical Investigation has uncovered why older individuals with specific genetic mutations face a heightened risk of developing serious blood cancers.
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Investigating Treatments for Peripheral Artery Disease
A common diabetes medication does not help people with peripheral artery disease (PAD) walk farther, according to results from a major U.S. clinical trial published in JAMA.
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Experimental Drug Shows Promise for Rare Genetic Disorder
A new experimental therapy has shown encouraging results in treating a rare and progressive lysosomal storage disorder, according to findings from a multi-year clinical trial published in the New England Journal of Medicine.
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New Treatment Directions for Rare Brain Disorder
A Northwestern Medicine study has uncovered a promising new therapeutic approach for a rare genetic brain disorder, according to findings published in Nature Communications.
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Novel Mechanism Regulates Essential Enzyme Production in Kidneys
Scientists have discovered previously unknown cellular mechanisms that regulate the production of renin, an essential enzyme in the kidney, findings that could improve the understanding of how the kidney regulates its function and how chronic kidney disease develops, according to a recent study published in Cell.
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Investigating HIV’s Hidden Immune Evasion Strategy
A Northwestern Medicine study published in Nature Communications has revealed how HIV can protect infected cells by altering the sugars on their surface, hindering the host immune system and avoiding detection.
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Understanding the Link Between Nucleotide Metabolism and Chromatin Assembly
A Northwestern Medicine study has revealed a connection between two fundamental cellular processes, offering fresh insight into how human cells build and maintain chromatin, according to findings published in Molecular Cell.
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Scientists Map the Human Genome in 4D
In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date of the genome’s three‑dimensional organization across time and space, according to a new study published in Nature.
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Exploring the Connection Between Gene Expression and Aging
Northwestern Medicine scientists have discovered how molecular “traffic controllers” in cells influence aging and cellular senescence — a state where cells stop dividing but remain metabolically active.
