Year: 2024
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Outsmarting Chemo-Resistant Ovarian Cancer
Northwestern Medicine scientists have discovered the Achilles heel of chemotherapy-resistant ovarian cancer — its hunger for cholesterol — and how to sneakily use that to destroy it.
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Engineered Heart Cells May Improve Understanding of Atrial Fibrillation
A multidisciplinary team of investigators have engineered a more accurate model for studying the underlying mechanisms of atrial fibrillation and treatment response, according to findings published in Science Advances.
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Novel Pathway Explains the Escalation of Fear Responses
Scientists have discovered a neuronal pathway involved in how the brain encodes the transition to high-intensity fear response behaviors required for survival, according to a study published in Nature.
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Calming Neurotransmitter Can Also Be Excitatory
A neurotransmitter previously thought to only calm neurons may also play a role in waking them up, according to a study published in the journal PLOS Biology, a discovery which upends conventional theories of how the neurotransmitter works in the brain.
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Analysis of K99/R00 Pipeline Illustrates Systematic Disadvantages
An analysis of NIH training grants has illustrated systematic disadvantages among the trainees who receive the awards.
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Study Shows Tiny ‘Twisters’ Move Cytoplasm Within Cells
Investigators at Northwestern Medicine and the Flatiron Institute have characterized how developing cells reorganize their cytoplasm as part of their growth, according to a study published in Nature Physics, a discovery which furthers the field’s understanding of basic cellular processes at the earliest stages of development.
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Neuronal Diversity Impacts the Brain’s Information Processing
Northwestern Medicine investigators have revealed new insights into the impact of neuronal structural diversity on neural computation, the basis of brain function, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Rethinking the Burden of Cancer Treatments’ Side Effects
Even mild and moderate side effects can contribute to patients with cancer discontinuing their treatment, according to an analysis recently published in the Journal of Clinical Oncology.
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Genes May Predict Treatment Resistance in Prostate Cancer
Increased expression of specific genes in prostate cancer patients may predict whether or not the cancer will respond well to hormone therapy, according to a new study published in Nature Communications.
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Immune Genes Are Altered in Alzheimer’s Patients’ Blood
A new study has found the immune system in the blood of Alzheimer’s patients is epigenetically altered, and many of these altered genes are the same ones that increase an individual’s risk for Alzheimer’s.
