Feinberg
Northwestern Medicine | Northwestern University | Faculty Profiles

News Center

  • Categories
    • Campus News
    • Disease Discoveries
    • Clinical Breakthroughs
    • Education News
    • Scientific Advances
  • Press Releases
  • Media Coverage
  • Podcasts
  • Editor’s Picks
    • COVID-19
    • Cardiology
    • Cancer
    • Neurology and Neuroscience
    • Aging and Longevity
    • Artificial Intelligence in Medicine
  • News Archives
  • About Us
    • Media Contact
    • Share Your News
    • News Feeds
    • Social Media
    • Contact Us
Menu
  • Categories
    • Campus News
    • Disease Discoveries
    • Clinical Breakthroughs
    • Education News
    • Scientific Advances
  • Press Releases
  • Media Coverage
  • Podcasts
  • Editor’s Picks
    • COVID-19
    • Cardiology
    • Cancer
    • Neurology and Neuroscience
    • Aging and Longevity
    • Artificial Intelligence in Medicine
  • News Archives
  • About Us
    • Media Contact
    • Share Your News
    • News Feeds
    • Social Media
    • Contact Us
Home » Common Gene Increases Prostate Cancer Risk
Uncategorized

Common Gene Increases Prostate Cancer Risk

By medwebJan 1, 2006
Share
Facebook Twitter Email

December 27, 2005

Common Gene Increases Prostate Cancer Risk

CHICAGO—A common, inherited gene that predisposes one in eight people to development of certain forms of cancer, including breast, colon, and ovarian cancers, has been found by Northwestern University researchers to also increase prostate cancer risk—by 200 percent.

Boris Pasche, MD, and colleagues at The Robert H. Lurie Comprehensive Cancer Center of Northwestern University have been screening for the gene, TGFBR1*6A, in individuals with a personal and family history of breast and ovarian cancers and in colon cancer.

Based on the recent findings in prostate cancer, the TGFBR1*6A cancer susceptibility gene study at Northwestern has been amended to include patients with a family history of prostate cancer.

Dr. Pasche is assistant professor of medicine, Division of Hematology/Oncology, at Northwestern University’s Feinberg School of Medicine and Northwestern Memorial Hospital and director of the cancer genetics program at the Cancer Center.

Dr. Pasche’s previous research showed that carriers of the TGFBR1*6A gene have a 38 percent higher risk for breast cancer, a 20 percent higher risk for colon cancer, and a 41 percent higher risk for ovarian cancer.

Dr. Pasche also demonstrated that people with two copies of the gene (homozygotes) have a cancer risk that is twice as high as that in individuals with one copy of the gene (heterozygotes).

For example, women who carry two copies of the TGFBR1*6A gene have a 169 percent increased risk for breast cancer and women who carry one copy of the gene have a 23 percent increased risk for breast cancer.

Dr. Pasche’s co-researchers on the genetic screening study are Virginia Kaklamani, MD, assistant professor of medicine, and Taya Fallen, a genetic counselor with the cancer genetics program.

The TGFBR1*6A studies at Northwestern are open to men and women and especially siblings, parents, and adult children (over 18 years) of individuals with a diagnosis of breast, colon, ovarian, or prostate cancer.

Study participants will be asked to provide a blood sample and will be contacted for a medical history and follow-up.

For information, call the cancer genetics program at 312/695-0320.

Share. Facebook Twitter Email

Related Posts

Mar 29, 2023

Adolescent Sexual Health Program Receives Funding for Social Marketing Campaign

Mar 29, 2023

Lurie Cancer Center Receives Merit Extension from NCI

Oct 20, 2021

Drug Combination May Reduce Risk of Leukemia Relapse

Mar 26, 2020

Comments are closed.

Latest News

Transcription Factor Prevents Bone Frailty in Chronic Kidney Disease

Jun 2, 2023

Study Establishes Fluctuating ’Gating’ Mechanisms Supporting Flexible Behavior

Jun 1, 2023

Discussing New Frontiers in Biomedicine

Jun 1, 2023

Reducing Seizures After Brain Tumor Treatment

May 31, 2023

Northwestern Accepting Nominations for $350,000 Nemmers Prize in Medical Science

May 30, 2023
  • News Center Home
  • Categories
  • Press Release
  • Media Coverage
  • Editor’s Picks
  • News Archives
  • About Us
Flickr Photos
ANB05555
ANB08990
ANB09022
ANB09063
ANB09008
ANB08781
ANB08971
ANB09000
ANB08992
ANB09015
ANB09058
ANB09048

Northwestern University logo

Northwestern University Feinberg School of Medicine

RSS Facebook Twitter LinkedIn Flickr YouTube Instagram
Copyright © 2023 Northwestern University
  • Contact Northwestern University
  • Disclaimer
  • Campus Emergency Information
  • Policy Statements

Type above and press Enter to search. Press Esc to cancel.