
With a new $20 million grant from the National Institute on Aging, Northwestern Medicine investigator, Linda Teplin, PhD, is extending the work of the Northwestern Juvenile Project to study the long-term consequences of incarceration on age-related conditions, including Alzheimer’s and other age-related diseases. This project is the only large-scale longitudinal study of its kind tracking…

The MYC oncogene is known in cancer research for aggressive cancers like treatment-resistant prostate cancer. Sarki Abdulkadir, MD, PhD, shares how his team uncovered compounds that block MYC gene activity.

Jeffrey Gordon, MD, often called “the father of microbiome research,” is the 2024 recipient of the Nemmers Prize in Medical Science. The Nemmers Prize of $350,000 is awarded to a biomedical scientist whose work exhibits outstanding achievement in medical science, as demonstrated by works of lasting significance.

New research from Issam Ben-Sahra, PhD could rewrite textbooks on our understanding of cellular metabolism and identify new targets for cancer and metabolic diseases such as obesity.

Nearly one million people in the U.S. are living with Parkinson’s disease, a condition for which there is still no known cause or cure. Joseph Mazzulli, PhD, has led two recent studies published in Neuron and Nature Communications uncovering previously unknown cellular mechanisms driving the disease.

For decades, Marcus Peter, PhD, has drilled into an area of research focused on cell death and the roles of toxic and protective short RNAs, with the goal of developing a novel form of cancer treatment. Now, this same line of research has led Peter’s team to uncover new insights into the cause of Alzheimer’s…

Northwestern Medicine physician-scientist Jaehyuk Choi, MD, PhD, discusses breakthrough in T-cell research for lupus. Choi and his lab members’ findings elucidate the underlying mechanisms of lupus and suggest therapeutic strategies.

A team of Northwestern Medicine scientists are conducting a new longitudinal cross-sectional study to investigate why some people see to age faster than others. In this episode, John Wilkins, MD, associate director of the Human Longevity Laboratory at the Potocsnak Longevity Institute, shares details of the study, which will eventually include a variety of interventions…

An estimated 32,000 Americans are currently living with ALS, or amyotrophic lateral sclerosis, a progressive neurodegenerative disease that attacks motor neurons in the brain and spinal cord. Northwestern investigators have uncovered novel cellular mechanisms involved in two types of genetic ALS that might lead to future targeted therapies. Evangelos Kiskinis, PhD, shares insights…

Northwestern Medicine scientists are at the forefront of research investigating the most effective ways of treating obesity in children and teens and improving their access to care. In this episode, Justin Ryder, PhD, a clinical and translational obesity scientist at Feinberg, talks about the use of new GLP-1–based medications for childhood obesity and his…