Tag: Neurosurgery
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Blood-Brain Barrier Disruption Reveals Genetic and Structural Changes in Neurological Diseases
Northwestern Medicine investigators have discovered unique genetic and structural changes in endothelial cells in the brain after disrupting the blood-brain barrier, which may inform new therapeutic targets that promote blood-brain barrier repair after neurovascular injuries, according to a recent study.
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Investigators Discover New Therapeutic Target for Pediatric Brain Cancers
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Drug Reprograms Immune Responses to Target Glioblastoma
Investigators have discovered that using a novel drug agonist to target the STING pathway in preclinical models of glioblastoma reprogrammed previously suppressed immune responses, according to recent findings published in the Journal of Clinical Investigation.
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New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells
Northwestern Medicine scientists have used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy, a major advance for the treatment of this deadly cancer.
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Novel Therapy Extends Survival in Metastatic Cancer
Northwestern Medicine investigators have identified a novel therapeutic agent that is effective in treating metastatic cancer and brain metastases, according to a recent study published in the Journal of Clinical Investigation.
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Study Identifies Genetic Cause for Some Brain Tumors
Scientists have uncovered a genetic explanation for a subset of common brain tumors, according to a study published in Nature Communications.
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Brain Tumor SPORE Receives $10.8 Million NCI Award Renewal
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a renewed five-year $10.8 million Specialized Program of Research Excellence (SPORE) grant from the National Cancer Institute for the Lurie Cancer Center to advance translational research and improve outcomes for patients with brain cancer.
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Developing New Nanoparticle Treatments for Brain Tumors
Northwestern Medicine investigators have developed a novel nanoparticle treatment for glioblastoma, according to a study published in Nature Communications.
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Study Identifies Enzyme that Helps Tumors Evade the Immune System
Northwestern Medicine scientists have identified an enzyme which aids tumors in evading the immune system, findings that could provide future directions for tumor treatment, according to a study published in Nature Communications.
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First Transient Electronic Bandage Speeds Healing by 30 Percent
Northwestern University scientists have developed a first-of-its-kind small, flexible, stretchable bandage that accelerates healing by delivering electrotherapy directly to the wound site.
