Tag: Neurosurgery
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Targeting STING Pathway Triggers Cytotoxic and Immune Responses Against Meningioma
Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Communications.
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Non-invasive Approach Predicts Chemotherapy Response in Glioblastoma
Northwestern Medicine scientists have developed a new non-invasive approach that could help better determine which patients with glioblastoma are responding favorably to chemotherapy treatment and inform future treatment plans, according to a recent study published in Nature Communications.
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Noninvasive Treatment Boosts Immune Response Against Glioblastoma
Northwestern Medicine scientists, along with collaborators from the Washington University School of Medicine, have developed a noninvasive nanomedicine approach that may improve the treatment of glioblastoma, according to a recent study published in the Proceedings of the National Academy of Sciences.
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Minimally Invasive Surgery May Improve Outcomes in Severe Stroke
Minimally invasive endoscopic surgery may be an effective and safe treatment for patients with intracerebral hemorrhage, the most severe type of stroke, according to results from a recent clinical trial published in JAMA Neurology.
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Diabetes Drug May Serve as Alternative Treatment Option for Hydrocephalus
A drug commonly used to treat diabetes may reduce excess fluid in the brains of patients with hydrocephalus, which could help treat the disease less invasively than current treatments, according to a study published in the Journal of Clinical Investigation.
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Blood-Brain Barrier Disruption Reveals Genetic and Structural Changes in Neurological Diseases
Northwestern Medicine investigators have discovered unique genetic and structural changes in endothelial cells in the brain after disrupting the blood-brain barrier, which may inform new therapeutic targets that promote blood-brain barrier repair after neurovascular injuries, according to a recent study.
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Investigators Discover New Therapeutic Target for Pediatric Brain Cancers
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
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Drug Reprograms Immune Responses to Target Glioblastoma
Investigators have discovered that using a novel drug agonist to target the STING pathway in preclinical models of glioblastoma reprogrammed previously suppressed immune responses, according to recent findings published in the Journal of Clinical Investigation.
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New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells
Northwestern Medicine scientists have used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and immunotherapy, a major advance for the treatment of this deadly cancer.
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Novel Therapy Extends Survival in Metastatic Cancer
Northwestern Medicine investigators have identified a novel therapeutic agent that is effective in treating metastatic cancer and brain metastases, according to a recent study published in the Journal of Clinical Investigation.
