Northwestern Medicine investigators have discovered new molecular mechanisms underlying DNA repair dysregulation in cancer cells, findings that may inform the development of new targeted therapies for patients that have become resistant to standard treatments.
Acceptance and commitment therapy significantly decreased fatigue interference and improved quality of life in patients with metastatic breast cancer six months after treatment, according to recent findings published in the Journal of Clinical Oncology.
Patients with a subtype of glioblastoma who received a combination treatment of a PARP inhibitor and standard chemotherapy did not demonstrate improved survival compared to chemotherapy and placebo, according to a recent clinical trial published in JAMA Oncology.
A type of immunotherapy appears to be effective in treating a deadly subset of thyroid cancer, according to the results of a clinical trial published in JAMA Oncology.
Just two years out from its launch, the Center for Human Immunobiology has quickly become a bustling hub for collaborative efforts to understand the molecular mechanisms of the immune system and translate discoveries into innovative cures for immune-regulated diseases.
Northwestern Medicine scientists have discovered how a protein in a deadly type of lung cancer can control how the immune system responds to the tumor, according to a study published in the Proceedings of the National Academy of Sciences.
The average length of survival for glioblastoma has failed to improve since it was first identified in scientific literature nearly 100 years ago. Despite this, scientists at Feinberg remain steadfast in their commitment to improving the understanding and treatment of glioblastoma through rigorous research initiatives and clinical trials.
Northwestern Medicine investigators have discovered that a novel combination treatment promotes cancer cell death and tumor regression in mouse models of pancreatic cancer, providing a rationale for testing in future clinical trials, according to recent findings.
Investigators have discovered that targeting specific mechanisms linked to lipid metabolism in immune cells within tumors may improve response to current and future cancer immunotherapies, according to a recent study published in the journal Immunity.
Patients receiving palliative care via telehealth report similar quality-of-life scores compared to those who had in-person care, according to a multicenter clinical trial recently published in JAMA.