Tag: Cancer
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Gene Linked to Glioblastoma Stem Cell Self-Renewal and Immunosuppression
Northwestern Medicine scientists have identified how one gene connects glioblastoma stem cell self-renewal to microglia immunosuppression in glioblastoma, according to a new study published in Nature Immunology.
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Investigating the Link Between Iron Deficiency and Regulation of Cell Growth
Northwestern Medicine investigators have uncovered new mechanisms by which iron deficiency inhibits cell growth and proliferation in eukaryotic cells, findings that could improve the understanding of cancer growth and the development of targeted cancer therapies.
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Combination Immunotherapy Shows No Additional Benefit for Most Advanced Cancers
A combination immunotherapy treatment of nivolumab plus ipilimumab was associated with no improvement in survival for advanced cancers other than melanoma, when compared to nivolumab alone, according to a recent Northwestern Medicine meta-analysis published in JAMA Oncology.
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Novel Intercellular Signaling Mechanisms Promote Melanoma Growth
Investigators have discovered novel intercellular “crosstalk” between epidermal keratinocytes and melanoma cells that promotes cancer growth and metastasis, which could also serve as biomarkers for early cancer detection, according to a recent Northwestern Medicine study.
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Protein Controls Lymphoma Cell Metabolism, Promotes Cancer Growth
Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
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Study Identifies Novel Cellular Mechanisms Promoting Growth of Uterine Fibroids
Northwestern Medicine investigators have discovered a novel molecular pathway that promotes tumor growth in uterine fibroids, findings that could inform the development of new targeted therapies, according to a recent study.
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Ion Channel Linked to Brain Inflammation Identified
Northwestern Medicine investigators have identified how a calcium channel in the nervous system contributes to brain inflammation, according to a study published in Nature Communications.
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Engineered Probiotic Can ‘Sense’ Inflammatory Bowel Disease
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
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Cella Named 2023 Tripartite Prize Recipient
David Cella, PhD, professor of Medical Social Sciences, has been named the winner of the 2023 Tripartite Legacy Faculty Prize in Translational Science and Education.
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Understanding Mechanisms Underlying Skin Development
Northwestern Medicine scientists have revealed how a gene considered essential for histone modification regulates skin development, according to a recent study published in Nature Communications.
