-
Understanding the Molecular Players in Eye Inflammation
Northwestern Medicine investigators have shed new light on how white blood cells in the retina function during inflammation and possibly during retinal vascular diseases with inflammatory components like diabetic retinopathy, according to a study recently published in the Journal of Clinical Investigation.
-
First-of-its-Kind Program Makes Organ Transplants More Accessible to Disadvantaged Black Americans
A recent publication has outlined the novel and practical approach to improving transplant equity pioneered by Northwestern’s African American Transplant Access Program.
-
Molecular Profiling May Improve Meningioma Decisionmaking
Investigators have demonstrated how molecular profiling of tumors can be used to help predict treatment response and survival in patients with meningiomas, the most common type of primary brain tumor, according to a recent study published in Nature Medicine.
-
Spike Mutations Help SARS-CoV-2 Infect the Brain
Northwestern Medicine scientists have discovered a mutation in SARS-CoV-2, the virus that causes COVID-19, that plays a key role in its ability to infect the central nervous system, according to recent findings.
-
Combination Treatment Improves Progression-Free Survival in Advanced Prostate Cancer with Genetic Mutations
A combination therapy improved progression-free survival in patients with metastatic castration-resistant prostate cancer with genetic mutations compared to either therapy alone or sequentially, according to results from a Northwestern Medicine-led clinical trial.
-
T-cell Responses Influence Patient Outcomes in SARS-CoV-2 Pneumonia
Northwestern Medicine investigators have identified distinct T-cell responses associated with patient outcomes in unvaccinated individuals with severe SARS-CoV-2 pneumonia, according to findings published in Nature Immunology.
-
One Minute to Save Lives: Teaming Up With Pediatricians to Secure Firearms
Scientists have found that pediatricians are more likely to have conversations with parents about gun safety and secure storage if they receive a “nudge” from an electronic health record.
-
Non-Neuron Brain Cells Produce a Third of Amyloid Plaque in Alzheimer’s Disease
An international team of investigators have discovered that oligodendrocytes contribute approximately one-third of plaque formation alongside neurons in mouse models of Alzheimer’s disease, according to a recent study published in Nature Neuroscience.
-
Northwestern Receives $55 Million to Advance Health Research
The Northwestern University Clinical and Translational Sciences (NUCATS) Institute has received $55 million in National Institutes of Health (NIH) funding to accelerate development, evaluation and implementation of improved healthcare interventions.
-
Oncoprotein Activity Increases Prostate Cancer Progression
Investigators have discovered that aberrant activation of a specific oncoprotein drives key tumor promoting changes in the prostate tissue microenvironment during cancer progression, according to a Northwestern Medicine study published in Nature Communications.
-
Older Adults in Illinois at Increased Risk for Suicide
Nearly 20 percent of suicides in Illinois between 2020 and 2021 were among people 65 years and older, according to recently released data.
-
Understanding Structural Drivers of HIV and Substance Use
The NIH recently funded the five-year SILOS Project, led by principal investigator Michelle Birkett, PhD, which will conduct innovative observational research across five cities across the United States to better understand the social contexts that drive HIV and substance use.
-
Hauser Named 2024 Tripartite Prize Awardee
Alan Hauser, MD, PhD, professor and vice chair of Microbiology-Immunology, has been named the winner of the 2024 Tripartite Legacy Faculty Prize in Translational Science and Education.
-
New Biomaterial Regrows Damaged Cartilage in Joints
A new bioactive material developed by Northwestern scientists may be able to regenerate high-quality cartilage in knee joints, according to a new study.
-
Investigating the Molecular Mechanisms of ‘Forgetting’
Northwestern Medicine investigators have uncovered a new way in which neurons in the brain “forget” associations that help guide behavior and habits, according to a study published in Cell Reports.
-
Intercellular Mechanisms Regulate Gene Expression in Cancer Cells
Scientists have discovered how interactions between RNA and the TOP1 essential enzyme, which is overexpressed in many human cancers, regulate DNA during transcription and may inform the creation of new cancer therapies, according to a Northwestern Medicine study published in Molecular Cell.
-
Advancing Pain Medicine Through Innovative Treatments and Precision Care
Get to know Steven P. Cohen, MD, who recently joined Northwestern University Feinberg School of Medicine as the inaugural Edmond I. Eger Professor of Anesthesiology and vice chair of Research and Pain Medicine.
-
Investigators Discover New Therapeutic Target for Pediatric Brain Cancers
Northwestern Medicine investigators have discovered that targeting the TIM3 protein in mouse models of low-grade astrocytoma increased survival compared to current immunotherapies, according to recent findings published in the Journal of Clinical Investigation.
-
Intense Exercise Doesn’t Increase Risk of Sudden Death in Genetic Heart Disorder
High-intensity exercise does not increase the risk of sudden cardiac death in individuals with congenital long-QT syndrome, a genetic heart disorder, according to findings from a recent study published in Circulation.
-
Study Identifies Racial Differences in Rare Endometrial Cancer
Northwestern Medicine investigators have discovered that uterine serous carcinoma tumors in Black patients express more aggressive and immunosuppressive features than tumors in white patients, according to a recent study published in the Proceedings of the National Academy of Sciences.
