Category: Disease Discoveries
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Leading Prostate Cancer Research for More than 20 Years
Prostate cancer is the most common type of cancer in men and is currently the second-leading cause of death in men in the U.S. In 2001, the National Cancer Institute established seven Specialized Programs of Research Excellence (SPORE) in prostate cancer across the U.S., one of which includes the Robert H. Lurie Comprehensive Cancer Center…
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B-Cells May Play Role in Lung Transplant Rejection
B-cells infiltrating the lungs may be responsible for one of the most common complications in lung transplantation that can lead to rejection, according to a study published in the Journal of Clinical Investigation.
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Study Discovers Potential Biomarkers of Environmental Exposures in Parkinson’s Disease
A team of Northwestern Medicine investigators has discovered novel DNA methylation patterns in the blood of patients with Parkinson’s disease, findings that demonstrate the potential for using DNA methylation as a biomarker to identify the disease.
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Uncovering the Culprits of Neurodegenerative Disorders
Recent studies from Feinberg scientists have uncovered new insights into these disorders, elucidating the mechanisms behind Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis, or ALS.
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Potential Therapeutic Target for Small Cell Lung Cancer Discovered
Northwestern Medicine investigators have discovered that inhibiting a chromatin remodeling complex associated with a particular gene in small-cell lung cancer cells may decrease cancer cell differentiation and tumor growth, according to findings published in Nature Communications.
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Novel Mechanism Supports Antitumor Response and T-cell Survival
A recent Northwestern Medicine study has discovered a previously unknown molecular mechanism that supports antitumor responses and cell survival in cytotoxic immune cells, according to findings published in the Journal of Clinical Investigation.
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Investigating Mechanisms of Aggressive Glioblastoma Tumor Growth
Northwestern Medicine investigators have identified a metabolism-related gene that may play a role in recruiting immune cells to support the growth of aggressive brain tumors, according to a study recently published in Nature Communications.
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Study Explores Characteristics Associated with Poor COVID-19 Antibody Response
U.S. adults with certain socio-demographic and clinical characteristics may have weaker antibody responses to COVID-19 vaccination, according to a recent study published in Nature Communications.
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Novel Immune Inhibitor Associated with Glioma Progression
Northwestern Medicine investigators led by Amy Heimberger, MD, PhD, have discovered a new mechanism in which cancer-associated fibroblasts are associated with tumor grade and mediate immune suppression in glioma tumors.
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Study Uncovers Novel Mechanisms Behind Food Allergies
A recent Northwestern Medicine study sheds light on the mechanisms of a specific protein that is necessary for the production of IgA antibodies in the gut in response to food allergens, according to findings published in the journal Mucosal Immunology.
