Category: Disease Discoveries
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Protein Controls Lymphoma Cell Metabolism, Promotes Cancer Growth
Northwestern Medicine investigators have discovered how the PD-1 protein controls essential metabolic processes in tumor cells to promote cancer growth in T-cell non-Hodgkin lymphomas, according to a study published in Nature Cancer.
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Study Identifies Novel Cellular Mechanisms Promoting Growth of Uterine Fibroids
Northwestern Medicine investigators have discovered a novel molecular pathway that promotes tumor growth in uterine fibroids, findings that could inform the development of new targeted therapies, according to a recent study.
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Newly Discovered Trigger of Parkinson’s Upends Common Beliefs
A new study suggests that a dysfunction in neurons’ synapses leads to deficits in dopamine and precedes the neurodegeneration previously thought to cause Parkinson’s disease.
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Engineered Probiotic Can ‘Sense’ Inflammatory Bowel Disease
Northwestern Medicine scientists have developed an engineered probiotic capable of detecting inflammatory bowel disease, according to a study published in the Proceedings of the National Academy of Sciences.
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Gene Linked to HIV Viral Load in People of African Ancestry
Naturally occurring variations near the human gene CHD1L may be linked to lower HIV-1 viral load in people of African ancestry, according to a new international, multicenter study published in Nature.
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New Approaches for Genetic Parkinson’s Treatment
An experimental drug targeting a genetic variant linked to Parkinson’s disease had no effect on patients, according to the results of a new clinical trial published in The Lancet Neurology.
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Study Discovers Novel Therapeutic Target for Acute Respiratory Distress Syndrome
A new Northwestern Medicine study has discovered a novel therapeutic target and therapeutic agents for older patients with acute respiratory distress syndrome, according to recent findings published in Science Translational Medicine.
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Study Uncovers Relationship between HIV-1 Infection and Neurodegeneration
Northwestern Medicine scientists have discovered how HIV hijacks intracellular processes to proliferate and contribute to neurodegeneration, according to a new study published in Nature Communications.
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Understanding How ALS-Linked Gene Disrupts Neurons
Northwestern Medicine investigators have uncovered how the ALS-associated gene NEK1 disrupts neuronal function in a new study published in Science Advances.
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Advancing our Understanding Behind the Mechanisms of Pain
Today, more than 50 million adults in the U.S. suffer from chronic pain — pain lasting longer than three months — and is the most common reason why people seek medical attention, according to the Centers for Disease Control and Prevention (CDC).
