Category: Disease Discoveries
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Investigating the Pathogenesis of Rare Congenital Nerve Disorder
A new Northwestern Medicine study has uncovered previously unidentified intracellular mechanisms in the peripheral nervous system that cause Charcot–Marie–Tooth Type 2B disease, findings that may inform the development of new targeted therapies.
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Studies Identify Novel Underpinnings of Genetic ALS
A pair of recent studies from the laboratory of Evangelos Kiskinis, PhD, have uncovered novel cellular mechanisms that are involved in two types of genetic ALS, providing support for future development of targeted therapies to treat the disease.
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Feinberg Scientists Make New Discoveries at the Forefront of Food Allergy Research
Though treatments for allergies have historically been slow-going, recent research by Feinberg investigators has provided new hope for the future of allergy management.
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One Sleepless Night Can Rapidly Reverse Depression for Several Days
Northwestern scientists have discovered the cause of the ‘punch-drunk’ feeling associated with sleep deprivation, and have found that it also increased dopamine and synaptic plasticity in the brain.
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Study Identifies Genetic Cause for Some Brain Tumors
Scientists have uncovered a genetic explanation for a subset of common brain tumors, according to a study published in Nature Communications.
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Mutations in 11 Genes Linked to Deadly Prostate Cancer
Scientists have linked mutations in 11 genes with aggressive prostate cancer, according to the largest-ever study of its kind recently published in JAMA Oncology.
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Combining Immunotherapy and Radiation in Soft Tissue Sarcoma
Combining immunotherapy with radiation may be a promising treatment option for patients with advanced soft tissue sarcoma, according to the results of a Northwestern Medicine clinical trial published in JAMA Oncology.
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Protein-Like Polymers Illuminate the Path to Macular Degeneration Treatment
A new Northwestern study details the use of protein-like polymers to potentially combat neovascular age-related macular degeneration, a leading cause of blindness.
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Pre-Pregnancy Obesity Predicts Future Heart Health
A new Northwestern Medicine study has found obesity before pregnancy is the root cause of future cardiovascular disease, rather than pregnancy complications.
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Investigating the Role of DNA Damage in Cardiac Hypertrophy
A novel cellular pathway regulates DNA damage and structural changes in cardiomyocytes which contributes to the development of cardiac hypertrophy according to a Northwestern Medicine study published in Circulation.
