Investigators led by Pinelopi Kapitsinou, MD, have discovered that inhibiting the hypoxia-driven MCT4 protein in kidney endothelial cells may halt the progression of ischemic acute kidney injury to chronic kidney disease, according to a recent study published in the Journal of Clinical Investigation.
Investigators from the laboratory of Ali Shilatifard, PhD, have developed a novel technique to precisely and efficiently study gene regulation, which may accelerate the development of new therapeutic strategies, according to a recent study published in Molecular Cell.