A New Clue to ALS and FTD: Faulty Protein Disrupts Brain’s ‘Brake’ System

Side-by-side image shows control neurons from a recently published study (left) compared to neurons from the study with the mis-spliced KCNQ2 gene.

A new Northwestern study has uncovered how a key disease protein drives overactive nerve cells in neurodegenerative diseases like ALS and frontotemporal dementia.