Northwestern Medicine scientists have identified the unique targets of two enzymes that activate ubiquitination, a key modification of proteins that controls a variety of cellular processes.
Former and current colleagues, students and friends gathered to celebrated the career of Paula Stern, PhD, an authority on bone and mineral health research, and a respected leader and educator.
Northwestern Medicine scientists have demonstrated an alternate method of signaling used by proteins called group I metabotropic glutamate receptors, a finding that could be used to develop novel drug treatments for many neurological disorders.
A new study shows potential mechanisms leading to the activation of a mutated gene in autosomal dominant polycystic kidney disease.
Northwestern Medicine scientists co-authored a study that identified a blood cell not normally found in the healthy brain that can invade brain tissue after status epilepticus, a type of seizure, and contributes to inflammation.
Northwestern Medicine scientists have received a $7.5 million grant to study how genetic information from African American patients can predict their responses to medications.
New Northwestern Medicine research has shown that reprogrammed stem cells can be used to identify patients with cancer who are likely to experience a dangerous side effect of a common chemotherapy drug.
In a new study, patients treated with one-fourth of the dose of beta-blockers tested in large clinical trials had a 20 to 25 percent increase in survival, indicating that dosing likely needs to be personalized for patients to get the best benefit.
A trail of messenger molecules left behind by general immune system cells called neutrophils helps virus-specific T-cells reach tissues infected by influenza, reports a new study published in Science.
Northwestern Medicine scientists received a five-year, $3.9 million grant from the National Institutes of Health to determine the optimal drug doses for treating pregnant women with depression.