Hyewon Phee, PhD, assistant professor in Microbiology-Immunology, showed that a lack of the protein Pak2 in immune cells may lead to immunodeficiency in patients.
An enzyme called caspase-8 prevents the onset of autoimmune disease lupus when expressed by dendritic cells.
Kathryn E. Hulse, PhD, research assistant professor in Medicine-Allergy-Immunology, found that while men are more likely to have chronic rhinosinusitis with nasal polyps, women with the disease have a more severe form.
Celeste Mallama, a fourth-year graduate student, studies how the bacterium that causes Legionnaires’ Disease infects host cells.
Rosalind Ramsey-Goldman, MD, professor of Medicine-Rheumatology, recently published a paper in the American Journal of Cardiology that links plaque in the carotid artery of women with lupus to an increased risk of cardiovascular events.
Published in Science Translational Medicine, new high-impact research findings from scientists at Northwestern Medicine could produce novel approaches to treat the tissue scarring known as fibrosis.
Published in mBio, the findings offer the first evidence that seminal plasma may have a direct role in promoting the transmission of a sexually transmitted infection.
Part of the $8 million multinational TumAdoR project, the study investigates the CD73 enzyme, which is overexpressed in many different forms of the disease.
Christian Stehlik and colleagues have learned how the molecular sensors that detect viruses and trigger defensive inflammatory responses are controlled.
The discovery of an enzyme that is highly activated in cells from the joint fluid of rheumatoid arthritis patients may provide a new therapeutic target for the 1 million Americans affected by the disease.